A. Namvar, A. Hajizade, S. Nazarian, Davoud Sadeghi, M. R. Akbari, Yousof Tarverdizade
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Design and Recombinant Expression of a multiepitope Vaccine Candidate Against Pathogenic Species of Shigella
Results: The sub-cloning of the gene was confirmed using PCR reaction. Gene expression analysis showed that the desired protein had a suitable expression. Western blotting analysis confirmed the expression of the recombinant protein. Conclusion: The expressed and purified multi-epitope recombinant protein, containing the main epitopes of the common antigens of pathogenic Shigella species could be achieved as the first step to design a multiepitope vaccine candidate against shigellosis.
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