口腔神经纤维瘤:埃努古10年经验

M. Nwoga
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引用次数: 0

摘要

背景:神经纤维瘤(NF)是一种来源于雪旺细胞增殖的神经肿瘤。口服NF是罕见的,尼日利亚文献中也没有已知的研究。目的:研究埃努古某三级医院口腔NF的临床病理特征,并对文献进行复习。材料和方法:这是一项回顾性研究,于2012年4月至2022年3月在埃努古的一家三级卫生机构进行。对在口腔病理和口腔医学科就诊的患者的临床记录、X线片和组织病理学报告中的NF病例进行检查。使用描述性统计和卡方统计对数据进行分析,以确定变量之间的相关性。结果:口腔周围神经鞘肿瘤仅11例,全部诊断为NF,占897例口腔颌面活检的1.1%。孤立性口腔NF占90.9%,而9.1%与I型神经纤维瘤病有关。其中一例孤立性病例发生在成釉细胞瘤。肿瘤发病时的平均年龄为38±24.4岁(范围:8-85岁)。男女比例为1.8:1,11个病灶中有7个(63.6%)仅位于软组织部位。舌(27.3%)和下颌骨(27.3%的)是最常见的骨内和软组织部位。观察到疼痛(18.2%)和复发(54.5%)。结论:口腔NF是最常见的外周神经鞘肿瘤,发病率低,男性多发,多发于骨外。
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Oral Neurofibroma: 10-Year Experience in Enugu
Background: Neurofibroma (NF) is a neural tumour derived from the proliferation of Schwann cells. Oral NF is rare, and no known study exists in the Nigerian literature. Aims: The aim was to study the clinicopathologic features of oral NF in a tertiary hospital in Enugu and review of the literature. Materials and Methods: This was a retrospective study conducted in a tertiary health institution in Enugu from April 2012 to March 2022. The clinical records, radiographs, and histopathology reports of patients seen at the department of oral pathology and oral medicine were examined for cases of NF. The data were analyzed using descriptive statistics, and Chi-square statistics for association between the variables. Results: There were only 11 oral peripheral neural sheath tumours, and all were diagnosed as NF. These constitute 1.1% of 897 orofacial biopsies received. Solitary oral NF constituted 90.9% of cases, while 9.1% was associated with neurofibromatosis type I. One of the solitary cases occurred with ameloblastoma. The mean age at the onset of the tumour was 38 ± 24.4 years (range: 8–85 years). A male-to-female ratio of 1.8:1 was obtained, and a majority of lesions, 7 (63.6%) of 11, were located in soft tissue sites only. The tongue (27.3%) and the mandible (27.3%) were the most common intraosseous and soft tissue sites. Pain (18.2%) and recurrence (54.5%) were observed. Conclusion: Oral NF was the most common peripheral nerve sheath tumour, with a low prevalence, male predilection, and frequently extraosseous.
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来源期刊
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0.00%
发文量
65
审稿时长
20 weeks
期刊介绍: The Nigerian Journal of Medicine publishes articles on socio-economic, political and legal matters related to medical practice; conference and workshop reports and medical news.
期刊最新文献
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