伊朗东北部儿童急性中毒的流行病学和社会人口学特征

A. Alami, Maryam Aghaei, Sepideh Shayan Karkon, Raheleh ِDerafshi
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摘要

引言:发达国家的急性中毒约占所有儿童死亡的2%,发展中国家的死亡原因超过5%。中毒通常被定义为服用一种可能导致生物体受伤的物质。本研究的目的是确定在改善中毒预防、预后和管理方面重要的社会学因素。方法:本回顾性研究评估了2015年3月至2018年7月在伊朗戈纳巴德22巴赫曼医院儿科病房的1200名儿童。通过对包括流行病学和人口统计学特征在内的标准化文件进行个体检查来记录儿童信息,并在SPSS 21.0版中使用U检验卡方、Pearson相关分析和方差分析对数据进行分析。结果:急性中毒占参考病因的2.3%,平均年龄3.7±1.3岁。中毒儿童的平均年龄明显低于其他儿童(p值=0/002)。大多数病例是鸦片(ICD-10 T40.0X1)和美沙酮(ICD-10T40.3X1)的意外中毒。最常见的症状是神经系统疾病、呕吐、呼吸急促和心动过速。被诊断为中毒的儿童常见的临床症状包括:神经系统症状,包括癫痫发作、幻觉、嗜睡、意识下降和意识模糊(50%)、恶心和呕吐(25%)、呼吸急促和心动过速(7.1%),由于将严重中毒患者转诊到设备更完善的中心而产生的眼泪和幻觉(3.6%)在我们的中心没有死亡记录。结论:急性中毒是儿童最常见的突发事件之一。这项研究确定了儿童急性中毒的流行病学和人口统计学因素,将有助于改善未来项目的预防和管理。
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Epidemiological and Socio-Demographic Characteristics of Children with Acute Poisoning in Northeast of Iran.
Introduction:Acute Poisoning in the developed countries include about 2% of all childhood deaths and more than 5% cause of death in the developing countries. Poisoning usually is defined as taking a substance which can cause an organism becoming injured. The purpose of this study was to identify sociological factors that are important in improving prevention, prognosis, and management of poisoning.  Methods: This retrospective evaluated 1200 children in the pediatric ward of the 22 Bahman hospital, Gonabad, Iran, from March 2015 to July 2018. The information about Children was recorded by individual examination of the files in standardized forms including epidemiological and demographic features for statistical analysis and data were analyzed by using the U Test Chi square, Pearson correlation analysis and variance analysis in SPSS Version 21.0. Results: Acute poisoning included 2.3% of referring causes with mean age 3.7 ± 1.3 years. The mean age of poisoned children was significantly lower than other children (p value = 0/002). The majority of cases were accidental poisonings with opium (ICD-10 T40.0X1) and methadone (ICD-10 T40.3X1). Most common symptoms were neurological disorders, vomiting, tachypnea and tachycardia.Common clinical symptoms in children diagnosed with poisoning include: Neurological symptoms including seizures, hallucinations, drowsiness, decreased level of consciousness and confusion (50%), nausea and vomiting (25%), tachypnea and tachycardia (7.1%). Respiratory depression, meiotic pupil, shortness of breath, cough, tears and hallucinations (3.6%) due to referring severe toxic patients to more equipped center no death was recorded in our center. Conclusion: Acute poisoning is one of the most abudant emergencies in children. This study with identifying epidemiological and demographic factors of acute poisoning in children would help to improve prevention, and management of future programs.
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