HIV-1包膜糖蛋白n端七肽重复区Glu560突变有助于对病毒进入肽抑制剂的抗性

IF 2.7 3区 医学 Q3 VIROLOGY Retrovirology Pub Date : 2019-12-01 DOI:10.1186/s12977-019-0496-8
Chen Yuan, Jiaye Wang, Hai-Jiao Zhao, Yan Li, Di Li, H. Ling, Zhuang Min
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Mutations of Glu560 within HIV-1 Envelope Glycoprotein N-terminal heptad repeat region contribute to resistance to peptide inhibitors of virus entry
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来源期刊
Retrovirology
Retrovirology 医学-病毒学
CiteScore
5.80
自引率
3.00%
发文量
24
审稿时长
>0 weeks
期刊介绍: Retrovirology is an open access, online journal that publishes stringently peer-reviewed, high-impact articles on host-pathogen interactions, fundamental mechanisms of replication, immune defenses, animal models, and clinical science relating to retroviruses. Retroviruses are pleiotropically found in animals. Well-described examples include avian, murine and primate retroviruses. Two human retroviruses are especially important pathogens. These are the human immunodeficiency virus, HIV, and the human T-cell leukemia virus, HTLV. HIV causes AIDS while HTLV-1 is the etiological agent for adult T-cell leukemia and HTLV-1-associated myelopathy/tropical spastic paraparesis. Retrovirology aims to cover comprehensively all aspects of human and animal retrovirus research.
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