尼日利亚中北部急性心力衰竭患者的特征

J. Ogunmodede, P. Kolo, M. O. Bojuwoye, B. Dele-Ojo, A. J. Ogunmodede, A. Omotoso
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摘要

目的:心力衰竭(HF)是尼日利亚住院的重要原因。由于人口老龄化和HF流行病学的变化,HF越来越普遍。我们旨在分析因急性心衰入院的患者的社会人口学、临床和超声心动图(Echo)特征。这是迄今为止尼日利亚最大的心衰患者队列之一。方法:横断面设计。社会人口学、临床和回声数据来自尼日利亚中北部伊洛林大学教学医院455名AHF患者。结果:患者的平均年龄为58.9±15.7岁(男性年龄大于女性,P=0.006)。265名(58.2%)为男性,大多数患者年龄>60岁,4.8%的患者患有2型糖尿病。53.2%的患者出现在纽约心脏协会III期和IV期。中位住院时间为11天(IQR,6-17),院内死亡率为11.6%。高血压是最常见的病因因素(62.4%),其次是扩张型心肌病17.6%、风湿性心脏病6.6%、围产期心肌病5.3%等。结论:我们研究中的AHF患者比尼日利亚和撒哈拉以南非洲先前研究中的患者年龄更大。高血压是AHF的主要驱动因素,患者大多患有临床晚期疾病,因此需要加强有关风险因素和早期表现的公共卫生教育。
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Characteristics of patients with acute heart failure in North Central Nigeria
Objectives: Heart failure (HF) is an important cause of hospital admission in Nigeria. HF is increasingly prevalent because the population is aging and HF epidemiology is changing. We aimed at profiling the socio-demographic, clinical and echocardiographic (Echo)  characteristics of patients admitted for acute HF. This is one of the largest cohorts of HF patients profiled in Nigeria so far. Methods: Cross sectional design. Socio-demographic, clinical and Echo data were collected from 455 patients admitted for AHF at University of Ilorin Teaching Hospital, North central, Nigeria. Results: Mean age of patients was 58.9± 15.7years, (men were older than women, P= 0.006). 265(58.2%) were males, most patients were aged >60 years, 4.8% had pre-existing Type2 Diabetes mellitus. 53.2% of patients presented in New York Heart Association Stages III and IV. Median duration of admission was 11days (IQR, 6-17), intrahospital mortality- 11.6%. Hypertension was the commonest aetiological factor (62.4%), followed by dilated cardiomyopathy 17.6%, rheumatic heart disease (6.6%), Peripartum cardiomyopathy (5.3%), and others. Conclusion: AHF patients in our study are older than those in previous studies in Nigeria and sub-Saharan Africa. Hypertension is main driver of AHF, and patients largely present with clinically advanced disease necessitating stronger public health education about risk factors and early presentation.  
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