献血者血源性病原体宏基因组学研究进展

国际输血及血液学杂志 Pub Date : 2019-09-20 DOI:10.3760/CMA.J.ISSN.1673-419X.2019.05.001

X. Dai, Gang Xu, Wei Hu

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引用次数: 0

摘要

血源性病原体可引起输血传播疾病。血站血源性病原体的检测能力与血液安全水平密切相关。探讨献血者血源性病原体的宏基因组学，有助于制定相应的输血传播疾病预防策略，提高血液安全。本文综述了血源性病原体宏基因组检测的技术和基本步骤，以及献血者的宏基因组数据。对血源性病原体宏基因组检测技术的发展进行了展望。关键词:血源性致病菌;Metagenome;高通量核苷酸测序;血;血液安全;献血者

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Advances in metagenomics techniques of blood borne pathogens in blood donors

Blood borne pathogens can cause transfusion transmitted diseases. The detection ability of blood borne pathogens in blood services is closely related to the level of blood safety. To explore the metagenomics of blood borne pathogens in blood donors is helpful to formulate corresponding prevention strategies for transfusion transmitted diseases and to improve blood safety. This article reviews the techniques and basic procedures of metagenome detection of blood borne pathogens, as well as the metagenome data in blood donors. The development of detection techniques in the blood borne pathogens metagenome is also prospected. Key words: Blood-borne pathogens; Metagenome; High-throughput nucleotide sequencing; Blood; Blood safety; Blood donors

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来源期刊

国际输血及血液学杂志

自引率

0.00%

发文量

10610

期刊介绍： The International Journal of Transfusion and Hematology was founded in September 1978. It is a comprehensive academic journal in the field of transfusion and hematology, supervised by the National Health Commission and co-sponsored by the Chinese Medical Association, West China Second Hospital of Sichuan University, and the Institute of Transfusion Medicine of the Chinese Academy of Medical Sciences. The journal is a comprehensive academic journal that combines the basic and clinical aspects of transfusion and hematology and is publicly distributed at home and abroad. The International Journal of Transfusion and Hematology mainly reports on the basic and clinical scientific research results and progress in the field of transfusion and hematology, new experiences, new methods, and new technologies in clinical diagnosis and treatment, introduces domestic and foreign research trends, conducts academic exchanges, and promotes the development of basic and clinical research in the field of transfusion and hematology.