多巴胺激动剂治疗侵袭性泌乳素瘤患者的冲动控制障碍:一例报告

P. Dutt
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引用次数: 0

摘要

催乳素瘤是垂体腺瘤的主要组成部分。所有有症状的泌乳素瘤都需要多巴胺激动剂(DA)治疗。冲动控制障碍(ICD)或病理行为是使用DA描述的罕见不良事件。在此,我们描述了一名男性患者在使用溴隐亭和更高剂量卡麦角林后进行病理性赌博和医生购物。在拆散手术、减少卡麦角林剂量和几次咨询后,病理行为消失了。开DA处方的医生应该意识到这种潜在的不良事件。在开始DA之前,应向患者和家属强调这一点,医生应在随访中好奇是否会引发病理行为。
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Impulse Control Disorder in a Patient with Invasive Prolactinoma on Dopamine agonist Therapy: A Case Report
Prolactinomas constitutes a major bulk of pituitary adenomas. All symptomatic prolactinomas require dopamine agonist (DA) therapy. Impulse control disorders (ICD) or pathological behaviours are rare adverse events described with use of DA. Herein we are describing a male patient with pathological gambling and doctor shopping following use of bromocriptine and higher dose of cabergoline.The pathological behaviour disappeard after debulking surgery, reduction in cabergoline dose and several sessions of counselling. Physicians prescribing DA should be aware of this potential adverse event.This should be emphasized to the patient and family members before starting DA and physician should be inquisitive for eliciting pathological behaviour on follow up.
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