Utilizing a neurosurgical hydrogel sealant (DuraSeal sealant) for the closure of bronchopleural fistulas: a case report of a novel technique

A bronchopleural fistula (BPF) is a pathological connection between the main stem, lobar, or segmental bronchus and the pleural space. This tract permits sterile pleural space to be contaminated, leading to a high risk of pleural space infections. In effect, morbidity and mortality remain high for this condition. There are quite a number of bronchoscopic interventions proposed to combat BPF’s. Even so, no technique has been found superior for closure of BPF’s to date. We present a challenging case report introducing the use of DuraSeal glue as a viable intervention for the termination of BPF’s. The glue has historically been used for the purpose of being a sealant and preventing cerebrospinal fluid leakage in cranial and spinal dural repair. Specifically, the material has provided a watertight seal allowing for the dura more time to heal compared to fibrin glue. To our knowledge, there have not been any previous reports of this specific glue being used to treat BPFs.