尼日利亚人口体重指数百分位数对骨骼成熟预测作用的估计。

O. Aghimien, Osasumwen Aghimien-Osaronse
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摘要

目的:探讨bmi指数百分位数对尼日利亚儿童骨骼成熟的预测作用。设计:前瞻性横断面研究。环境:本研究在尼日利亚中北部的一家三级卫生保健机构进行。参与者:年龄在5-17岁之间的儿童,包括44名男性和30名女性,他们在儿童牙科诊所就诊了8个月。测量的主要结果:使用第三指的中指骨(MP3)评估骨骼成熟度,而针对年龄(2-20岁)和性别的标准WHO生长图表用于bmi百分位数分级。采用非配对t检验比较不同性别MP3阶段的平均实足年龄。采用多项logistic回归确定年龄、性别和BMI百分位数对青春期生长突增的预测作用。结果:bmi百分位数与青春期生长突增呈弱相关(r=0.089, p=0.448)。性别(p=0.004)和实足年龄对骨骼成熟度有显著的预测作用(p<0.001)。与肥胖儿童相比,bmi -百分位数每增加一个百分位数,健康儿童处于青春期高峰的可能性就会降低1.504 (p=0.305)。结论:本研究表明bmi百分位数是骨骼成熟的弱预测因子。然而,肥胖儿童比健康儿童更倾向于骨骼成熟。因此,建议正畸医师应考虑在肥胖儿童中早期实施下颌矫正治疗。
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ESTIMATION OF THE PREDICTIVE EFFECT OF BODY MASS INDEX-PERCENTILE ON SKELETAL MATURATION IN A NIGERIAN POPULATION.
Objectives: To determine the predicting the effect of BMI-index percentile on the skeletal maturation of Nigerian children.  Design: A prospective cross-sectional study. Setting: This study was conducted in a tertiary health care facility in North-Central Nigeria. Participants: Children between the ages of 5-17 years consisting of 44 males and 30 females that presented in the Child Dental clinic over a period of eight months were recruited for the study. Main outcome measured: Skeletal maturation was assessed using the middle phalanx of the third finger (MP3) while the standard WHO growth chart specific for age (2-20 years) and gender was used for grading BMI-percentile. The unpaired t-test was used to compare mean chronological age of the stages of MP3 according to gender. Multinomial logistic regression used to determine the predictive effect of age, gender and BMI percentile on pubertal growth spurt. Results: The BMI-percentile had weak correlation with the pubertal growth spurt (r=0.089, p=0.448). Gender (p=0.004) and chronological age had significant (p<0.001) predictive effect on the skeletal maturation. A one-percentile increase in the BMI-percentile decreases the likelihood of healthy children to be in the peak-pubertal by 1.504 when compared to obese children (p=0.305).  Conclusions: This study showed that BMI-percentile is a weak predictor of skeletal maturation. However, obese children had a tendency towards advanced skeletal maturation than healthy participants. It is therefore suggested that orthodontists should consider early implementation of jaw modification treatments among obese children. 
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