评估不同年龄组BDNF与非侵入性神经衰退指标的相关性

S. Batool, F. Mirza
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引用次数: 0

摘要

背景:健康是现代社会最关心的问题,随着人类寿命的延长,人类的身心健康状况都在下降,最终影响到一个人的认知能力,这可能是由于正常的衰老过程或神经病理原因。一项横断面研究探讨了BDNF水平、神经障碍和衰老之间的关系。方法:通过语言流畅性测试(FAS, DSST和6CIT)和HPLC检测血液BDNF水平进行认知评估,采用elisa试剂盒方法。结果:连续变量采用描述性统计。因此,我们采用单因素方差分析来显示认知参数与衰老之间的关系。结论:我们的研究表明,尽管性别、教育、肥胖或生活方式不会影响认知,但随着寿命的增长,语言流畅性会受到干扰。
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Assessing BDNF correlations with non-invasive indicators of neurological decline in different age groups
Background: Health is the prime concern of the modern world, and with the increasing life span, both the physical and mental health of human being decline, eventually affecting the cognitive abilities of a person, which may be due to normal aging processes or neuropathological reasons. A cross-sectional study investigated the relationship between BDNF level, neurological disturbance, and aging. Methodology: Cognitive assessment is done through verbal fluency test (FAS, DSST, and 6CIT) and BDNF level in blood found through HPLC utilizing the ALIZA kit method. Results: Descriptive statistics were applied for continuous variables. Hence, one-way ANOVA was performed to show the relationship between cognitive parameters and aging. Conclusion: Our study reports that verbal fluency disturbs as lifetime increases, although sex, education, obesity, or lifestyle does not affect cognition.
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