阿尔茨海默病患者的急性尿毒症多神经病变

S. A. Mamykina, V. V. Oganov, O. N. Voskresenskaya, V. V. Grinyuk
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引用次数: 0

摘要

本文报告一例急性尿毒症神经病。一位71岁的病人在没有任何明显原因的情况下,感到双腿无力,双脚麻木。她入院时的神经系统状态评估显示周围性四肢麻痹和多神经病变型敏感性受损。肾功能不全引起神经系统症状,经实验室检查证实。神经肌电图显示急性脱髓鞘性多发性神经病的征象。Аt到医院后,患者被诊断为阿尔茨海默病。在医院提供的治疗使她的实验室参数正常化,运动功能完全恢复。本病例的特点是患者因认知障碍导致肾功能不全和急性尿毒症神经病变而开始违反饮酒规则。该病例的另一个特点是,在不使用透析的情况下,纠正水电解质紊乱足以在一个月内完全恢复患者的运动功能。最后,本文讨论了其他类型多发性神经病的发病机制和鉴别诊断问题。
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Acute uremic polyneuropathy in a patient with Alzheimer’s disease
The article presents a case of acute uremic neuropathy. Without any visible cause, a 71-year-old patient felt weakness in legs and numbness in feet. Her neurological status assessment on admission to the hospital showed peripheral tetraparesis and impaired sensitivity of the polyneuropathic type. Neurological symptoms appeared due to renal dysfunction, which had been confi rmed with laboratory test. Electroneuromyography revealed signs of acute demyelinating polyneuropathy. Аt the hospital, the patient was diagnosed Alzheimer’s disease. The treatment provided at the hospital led to normalization of her laboratory parameters and complete restoration of motor functions. The peculiarity of the presented clinical case is that the patient started violating drinking regime due to her cognitive impairment which resulted in renal dysfunction and acute uremic neuropathy. The other peculiarity of the case is that it was enough to correct the water-electrolyte disorders to fully restore the patient’s motor functions within a month, without the use of dialysis. Finally, the article discusses the issue of pathogenesis and diff erential diagnosis of other types of polyneuropathies.
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来源期刊
Russian Neurological Journal
Russian Neurological Journal Medicine-Neurology (clinical)
CiteScore
0.40
自引率
0.00%
发文量
49
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