儿童和青少年中与极低剂量抗精神病药物相关的横纹肌溶解和抗精神病药物恶性综合征

IF 2.4 4区医学 Q3 NEUROSCIENCES Clinical Psychopharmacology and Neuroscience Pub Date : 2019-08-01 DOI:10.9758/cpn.2019.17.3.450

Jong-Il Park, T. Park

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引用次数: 4

摘要

随着成人精神病学领域的发展，抗精神病药物越来越多地用于儿童和青少年精神病学领域。尽管抗精神病药物引起的抗精神病药恶性综合征（NMS）和横纹肌溶解症是罕见的并发症，但临床医生应注意所有潜在的药物不良反应（ADR）。此外，与成人相比，儿童和青少年的ADR可能表现出不同的体征和症状。在本病例报告中，我们报告了一例儿童NMS病例，该病例发生在低剂量利培酮诱导的横纹肌溶解症消退后不久。

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Rhabdomyolysis and Neuroleptic Malignant Syndrome Associated with Very Low-dose Antipsychotics in Children and Adolescent

Along with the field of adult psychiatry, antipsychotic agents are increasingly used in the field of child and adolescent psychiatry. Although neuroleptic malignant syndrome (NMS) and rhabdomyolysis are rare complication associated with antipsychotic agent, clinicians should need to pay attention to all potential adverse drug reaction (ADR). Also, ADRs in child and adolescent could show different signs and symptoms compared with those in adult. In this case report, we present a case of NMS in a child which occurred shortly after the resolution of rhabdomyolysis which was induced by low-dose risperidone.

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来源期刊

Clinical Psychopharmacology and Neuroscience NEUROSCIENCESPHARMACOLOGY & PHARMACY-PHARMACOLOGY & PHARMACY

CiteScore

4.70

自引率

12.50%

发文量

期刊介绍： Clinical Psychopharmacology and Neuroscience (Clin Psychopharmacol Neurosci) launched in 2003, is the official journal of The Korean College of Neuropsychopharmacology (KCNP), and the associate journal for Asian College of Neuropsychopharmacology (AsCNP). This journal aims to publish evidence-based, scientifically written articles related to clinical and preclinical studies in the field of psychopharmacology and neuroscience. This journal intends to foster and encourage communications between psychiatrist, neuroscientist and all related experts in Asia as well as worldwide. It is published four times a year at the last day of February, May, August, and November.