一项评估体外冲击波碎石与输尿管镜治疗输尿管近端5 - 10mm结石疗效的前瞻性研究

B. Rayamajhi, A. Khadka, N. Thapa
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引用次数: 1

摘要

导读:输尿管上段结石的手术治疗有各种国际指南。对于小于10mm的输尿管上段结石,ESWL和URS被视为一线治疗。然而,在我们的环境中,缺乏适当的手术选择的国家指南。方法:采用前瞻性比较法,将100例患者分为ESWL组和URS组,每组各50例。超声和非增强计算机断层扫描确认结石大小后行ESWL和URS检查。所有患者在术后1周和6周接受x线KUB检查以确认结石清除。残余结石小于5mm者认为无结石。使用graphpad prism版本6进行统计分析。结果:ESWL组和URS组患者的平均年龄分别为41.28±15.3岁和42.84±16.1岁。ESWL组的男女比例较高。ESWL前的平均粒径为8.58 mm, URS前的平均粒径为8.44 mm。ESWL在1周和6周时结石清除率分别为56%和90%,而URS在1周和6周时结石清除率均超过90%。URS的并发症发生率(20%)高于ESWL(8%)。结论:ESWL和URS在清除结石方面同样有效。ESWL组持续时间更长,URS组并发症较多。
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A Prospective Study to Assess the Effectiveness of Extracorporeal Shock Wave Lithotripsy Versus Ureteroscopy for Proximal Ureteral Calculi Between Sizes 5 to 10 mm
Introduction: There are various international guidelines for the surgical treatment of upper ureteral calculi. For upper ureteral stone of less than 10 mm size, ESWL and URS are regarded as first line treatment. However, there is lack of national guidelines for appropriate surgical options for such stone in our settings. Methods: The study was prospective comparative type involving 100 patients who were divided into ESWL and URS groups comprising 50 patients in each. ESWL and URS were performed after confirmation of stone size with ultrasonography and non-contrast enhanced computed tomography. All patients underwent X-ray KUB at one week and six weeks post procedure for confirmation of stone clearance. Those with residual calculi of size < 5 mm were considered stone free. Statistical analysis was done using Graph pad prism version 6. Results: The mean age of patients in ESWL and URS groups were 41.28 ± 15.3 years and 42.84 ± 16.1 years respectively. The male to female ratio was higher in ESWL group. The mean size of the stone pre ESWL was 8.58 mm and pre URS was 8.44 mm. The percentage of stone clearance at one week and six weeks for ESWL was 56% and 90% respectively whereas for URS, it was more than 90% at both one week and six weeks. The complications were higher with URS (20%) than ESWL (8%). Conclusions: The ESWL and URS are equally effective in stone clearance. The duration is longer with ESWL and the complications were more in URS group.
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