Tissue Fragility and Ehlers-Danlos Syndrome Global Aggravation by Osteopathic Manipulations

Ehlers-Danlos syndrome is a hereditary, diffuse connective tissue disorder whose frequency is largely underestimated. Its diagnosis rests on a grouping of clinical criteria while biogenetic results are unreliable. Paradoxically, Ehlers-Danlos syndrome is considered as a rare disease while its prevalence in the world is at least 2%. It is very poorly known and very rarely diagnosed. This situation is dangerous for patients and exposes them to iatrogenic effects. The case reported here is a good illustration of this situation in a 26-year-old man, with local complications (paralysis of serratus major), a dramatic worsening of the disease’s symptoms (pain, proprioception) and exclusion from the work world.