非激素干预对围绝经期妇女血脂的影响。

Muthulakshmi. C, Dr. S. Kalabarathi, Dr. Nithisharma
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引用次数: 0

摘要

本研究旨在发现一种非激素治疗的效果,以帮助解决围绝经期妇女的血脂异常。实现这一目标的目的是发现大豆补充剂对围绝经期血脂异常妇女低密度脂蛋白(LDL)、高密度脂蛋白(HDL)和总胆固醇(TCL)水平的影响。这项单盲准实验研究在印度南部的一个农村社区进行,有54名40-55岁的围绝经期妇女。研究对象被随机分为只接受结构化健康教育的对照组和接受结构化健康教育的试验组,并在每周3天的替代日补充50克豆粕咖喱,持续16周。研究的HDL、LDL和TCL水平的三结局分析分别在8周(后测试1)和16周(后测试2)后作为基线选择标准的一部分进行分析。研究结果显示,实验组三种生物标志物的归一化明显优于对照组。这项研究支持了大豆饮食可以作为雌激素治疗的辅助疗法的说法。因此,该研究倾向于使用大豆饮食作为治疗围绝经期妇女血脂异常的选择。
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Influence of Non-Hormonal Intervention On Lipid Profile Among Perimenopausal Women.
This study aims to find the effect of a non-hormonal therapy to help solve dyslipidemia among perimenopausalwomen. The objective of achieving this aim was to find the effect of soya supplementation on low-density lipoprotein (LDL),high-density lipoprotein (HDL), and total cholesterol (TCL) levels among perimenopausal women with dyslipidemia. This singleblindedquasi-experimental study was conducted in a rural community in southern India with 54 perimenopausal women in 40-55 age. The subjects were randomized into a control group that received only structured health education and an experimentalgroup that received structured health education, and soya supplements 50 grams of soya meal curry on alternative days for 3days a week for 16 weeks. The three-outcome analysis for the study HDL, LDL, and TCL levels was analyzed as a part ofbaseline selection criteria (Pre-test), following 8 weeks (Post-test 1) and 16th weeks (Post-test 2), respectively. The study resultsshowed that all three biomarkers normalized significantly better in the experimental group than in the control group. The studysupports the statement that a soya diet can be an adjunct to estrogen therapy. Hence, the study favors using a soya diet as atreatment choice for managing dyslipidemia among perimenopausal women.
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