α-PVP跨学科综述

İ. Afşin Kariper , Ahmet Metin , Kasim Büyükbezirci , Ayşe Eken , Elçin Bakir
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引用次数: 0

摘要

α-PVP已成为当今最危险的药物之一。α-PVP在化学上是脯氨酸的酮类类似物。在物理上,它是一种无味、无色的固体晶体形式。α-PVP在化学上也被称为α-吡咯烷酮戊烯酮、1-苯基-2-(吡咯烷-1-基)戊烷-1-酮、α-吡咯烷酮戊烯酮。在这项研究中,我们重点对这种在年轻人中非常流行的药物α-PVP进行了综述。研究主要集中在α-PVP的化学(合成、类似物)、理化(如密度、粘度、极性、表面张力)性质、药效学、药代动力学、毒性作用以及心理效应和预防研究。α-PVP玩家经常会出现意识丧失,呼吸困难,最糟糕的情况是死亡。它有很高的毒性。据了解,这种合成化学品可以在实验室环境和化学上大量生产。关于这些问题的文献信息通常收集在这篇概述文章中。在研究的结论部分,提出了α-PVP的负面影响,并提出了建议。
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An interdisciplinary overview of α-PVP

α-PVP has become one of the most dangerous drugs today. α-PVP is chemically the ketone analog of proline. Physically, it is an odorless, colorless solid crystal form. α-PVP is also chemically called α-pyrrolidinovalerophenone, 1-Phenyl-2- (pyrrolidine-1-yl) pentane-1-one, α-Pyrrolidinopentiophenone. In this study, we focused on a general review of this drug, α-PVP, which has become very popular among young people. The study mainly focused on the chemical (synthesis, analogs) and physicochemical (such as density, viscosity, polarity, surface tension) properties, pharmacodynamics, pharmacokinetics, and toxic effects of α-PVP, as well as psychological effects and preventive studies. α-PVP users often appear to cause loss of consciousness, difficulty breathing, and, worst cases, death. It has high toxicity. It has been understood that such a synthetic chemical can be produced in high amounts in a laboratory environment and chemically. The information in the literature on these issues is generally collected in this overview article. In the conclusion part of the study, the negative effects of α-PVP were mentioned, and suggestions were made.

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来源期刊
Revue de Medecine Legale
Revue de Medecine Legale Medicine-Pathology and Forensic Medicine
CiteScore
0.20
自引率
0.00%
发文量
26
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