Evaluating the effect of Clinpro Tooth Crème on remineralization of pre-carious White Spot Lesions in anterior primary teeth: Randomized controlled clinical trial

Background

New direction in dentistry has been developed to increase the minimal-invasive approach, especially in younger children. Therefore, needs has arise to find new techniques to replace the restorative and surgical treatments of dental caries with more conservative therapies. So that remineralization therapies has taken place in the last few years.

Materials and methods

A total of 84 teeth with white-spot lesions in 18, three-to-five-year-old children were included in the study. All of the selected teeth had no yellow or brown discoloration, no carious cavities or developmental defects, and gave the value of 5–17 when measured using DIAGNOdent.

Clinpro Tooth Crème was applied for 3 min after cleaning and drying on each tooth, a photograph was taken after every application with intervals of one week, two weeks, four weeks and six weeks. The laser fluorescence intensity was measured using DIAGNOdent before every application and 10 min after. The clinical appearance change was evaluated by calculating the ratio of the area of white-spot lesion to the whole area of buccal surface of each tooth using AutoCAD 2015. Results were statistically analyzed using Mann-Whitney and Kruskal-Wallis tests.

Results

Statistical analysis showed that there was an important significant differences between DIAGNOdent values of Clinpro group and the other group (p < 0.05), but no significant change in the ratio of the area of white-spot lesion to the whole area of buccal surface of the tooth (p > 0.05).

Conclusions

Clinpro Tooth Crème improved white-spot lesions remineralization but did not prettify clinical appearance after its application within the used protocol.