原发性高血压患者血清甘油三酯与高密度脂蛋白胆固醇比值与血压的相关性

IF 0.4 Q4 MEDICINE, RESEARCH & EXPERIMENTAL Precision Medical Sciences Pub Date : 2022-08-16 DOI:10.1002/prm2.12080
O. Kurtkulagi, G. Aktas, T. Taslamacioglu Duman, S. Bilgin, B. A. Atak Tel, G. Kahveci
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引用次数: 7

摘要

高血压(HT)与显著的发病率和死亡率相关。HT患者的治疗效果主要取决于办公室或家庭的血压监测。甘油三酯与高密度脂蛋白(HDL)胆固醇比率(THR)是炎症和代谢的预测指标。我们的目的是比较血压控制不佳的HT患者和血压控制良好的高血压患者的THR水平。在目前的横断面研究中,我们根据血压测量将HT患者与控制良好或控制不佳的高血压受试者分组。比较各组的THR。控制不佳的HT组的THR(3.9[1.91–88.7]%)显著高于控制良好的HT组(3.07[0.71–35.8]%)(p<.001)。高于3.26%的THR预测血压控制不佳的敏感性和特异性分别为72%和52%(AUC:0.64,p<.01,%95 CI:%59–70)。HT患者的高THR水平可能需要更密切地监测血压,因为这可能预示着该人群的血压控制不佳。
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Correlation between serum triglyceride to HDL cholesterol ratio and blood pressure in patients with primary hypertension
Hypertension (HT) is associated with significant morbidity and mortality. The efficacy of the treatment in HT patients is mostly depending on the office or home blood pressure monitoring. Triglyceride to high density lipoprotein (HDL) cholesterol ratio (THR) is an inflammatory and metabolic predictor. We aimed to compare THR levels of the HT patients with poorly controlled blood pressure levels to those with well‐controlled hypertensive subjects. In present cross sectional study, we grouped patients with HT either as well or poorly controlled hypertensive subjects according to the blood pressure measurement. THR of the groups compared. The THR of the poorly controlled HT group (3.9 [1.91–88.7]%) was significantly higher than the THR of the well‐controlled HT group (3.07 [0.71–35.8]%), (p < .001). The sensitivity and specificity of THR higher than 3.26% in predicting poor blood pressure control were 72% and 52%, respectively (AUC: 0.64, p <.01, %95 CI: %59–70). High THR levels in HT patients may warrant closer monitorization of blood pressure since it may predict poor blood pressure control in this population.
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来源期刊
Precision Medical Sciences
Precision Medical Sciences MEDICINE, RESEARCH & EXPERIMENTAL-
自引率
0.00%
发文量
33
审稿时长
15 weeks
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