Modulation of Bone Metabolism Markers Following Low-Repetition and Light-Load Power Training in Postmenopausal Women: A Randomized Controlled Trial

Abstract Introduction. The study aimed to survey effects of 6 weeks of low-repetition and light-load power training on serum Osteocalcin, Parathormone and Sclerostin in sedentary postmenopausal women. Material and Methods. This randomized controlled trial was carried out in healthy and sedentary postmenopausal women. We recruited 24 volunteers aged 55 to 65 years. Participants were allocated into two groups: experimental and control. The experimental group performed 6-week low-repetition and light-load power training at a frequency of three sessions per week. The outcome measures included Osteocalcin, Parathormone, Sclerostin. Blood samples were drawn pre- and post-intervention while fasting. Data were analyzed using SPSS19, and multivariate ANCOVA and Bonferroni post hoc test were used. Results. After 6 weeks of low-repetition and light-load power training, Sclerostin decreased (p = 0.03), while Osteocalcin and Parathormone increased (p = 0.01) in the training group compared to the control group. Conclusions. It seems that low-repetition and light-load power training, by increasing Osteocalcin and Parathormone and reducing Sclerostin, can be effective in bone formation in postmenopausal women.