金属配合物作为潜在的自由基中和剂的体外研究综述

Q4 Medicine Acta Medica Saliniana Pub Date : 2023-02-20 DOI:10.5457/ams.v52i1-2.618
Merima Imamović, E. Horozić, Vedad Salkovic, Armina Pasalic, Nermina Hadžić
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引用次数: 0

摘要

金属配合物因其抗菌、抗真菌、抗肿瘤和抗氧化的特性而受到广泛的研究。大量的金属配合物具有中和自由基的能力,自由基通常是由于体内代谢过程、吸烟、暴露于辐射和化学物质而产生的。测试金属配合物的抗氧化能力可以通过各种方法在体外和体内进行测试。本文将介绍近年来使用不同配体合成的金属配合物对自由基的中和效率,以及最常用的测试该类compounds.Â抗氧化能力的方法
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Metal complexes as potential agents for neutralizing free radicals: a review of in vitro studies
Metal complexes due to their antibacterial, antifungal, antitumor and antioxidant properties have been extremely studied today. A large number of metal complexes have the ability to neutralize free radicals, which most often occur as a result of metabolic processes in the body, smoking, exposure to radiation and chemical substances. Testing the antioxidant capacity of metal complexes can be tested by various methods in vitro and in vivo. This paper will present the efficiency of neutralization of free radicals by metal complexes synthesized in the past few years using different ligands, as well as the most commonly used methods for testing the antioxidant capacity of this group of compounds. 
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Acta Medica Saliniana
Acta Medica Saliniana Medicine-Medicine (all)
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