新生儿垂体柄中断综合征1例

Q4 Medicine 中华围产医学杂志 Pub Date : 2019-12-16 DOI:10.3760/CMA.J.ISSN.1007-9408.2019.12.010

Hui-ping Shi, L. Tao, Ning Zhao

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引用次数: 0

摘要

本研究报告了一名在妊娠43+2周通过剖宫产出生的足月女婴，出生体重为2950克。出生后14小时左右出现氰化物。实验室测试结果显示，血糖为1.4mmol/L，游离三碘甲状腺原氨酸（FT3）、游离四碘甲状腺原质酸（FT4）、促甲状腺激素（TSH）、生长激素（GH）和胰岛素样生长因子-1（IGF-1）水平显著降低。头颅MRI证实了垂体柄中断综合征的诊断。女婴接受氢化可的松和左甲状腺素治疗，在临床症状改善和血糖正常后出院。随访数据显示，出生后6个月和10个月血糖不稳定，甲状腺功能减退，15个月生长迟缓。关键词：垂体疾病；低血糖；甲状腺功能减退；婴儿、新生儿

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Pituitary stalk interruption syndrome in newborn: a case report

This study reported a postterm female infant born at 43+2 weeks of gestation via cesarean section with a birth weight of 2 950 g. Cyanosis was presented around 14 h after birth. Laboratory test results showed that the blood glucose was 1.4 mmol/L and the levels of free triiodothyronine (FT3), free tetraiodothyronine (FT4), thyrotropin (TSH), growth hormone (GH) and insulin-like growth factor-1 (IGF-1) were significantly reduced. Cranial MRI confirmed the diagnosis of pituitary stalk interruption syndrome. The baby girl was treated with hydrocortisone and levothyroxine and discharged following clinical symptoms improvement and blood glucose normalization. Follow-up data showed unstable blood glucose and hypothyroidism at six and 10 months after birth and growth retardation at 15 months. Key words: Pituitary diseases; Hypoglycemia; Hypothyroidism; Infant, newborn

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