临床药师干预对解决全身性自身免疫性疾病患者药物相关问题的影响

IF 0.4 Q4 PHARMACOLOGY & PHARMACY Journal of Pharmacology & Pharmacotherapeutics Pub Date : 2021-10-01 DOI:10.4103/jpp.jpp_149_21
S. Sah, Subramanian Ramaswamy, M. Ramesh
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引用次数: 1

摘要

系统性自身免疫性疾病是导致死亡和残疾的主要原因之一。它们包括一组异质性炎症性疾病,如类风湿性关节炎、系统性红斑狼疮(SLE)、系统性血管炎、硬皮病、银屑病和影响多器官系统的干燥综合征。[1] 由于慢性治疗方案和较高的疾病复发率,系统性自身免疫性疾病的药物治疗相当具有挑战性。[2] 复杂的药物方案与药物相关问题(DRPs)的高风险相关。[3] 由于DRPs正成为现代临床实践中的主要关注点之一,及时识别和解决DRPs对于降低治疗相关危害至关重要。可以通过优化药物治疗来提高患者满意度,减少经济和医源性负担。[4]
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Impact of Clinical Pharmacist Interventions in Resolving Drug-Related Problems in Patients with Systemic Autoimmune Disorders
Systemic autoimmune disorders are one of the leading causes of death and disability. They include a heterogeneous group of inflammatory diseases such as rheumatoid arthritis, systemic lupus erythematosus (SLE), systemic vasculitis, scleroderma, psoriasis, and Sjogren’s syndrome that affects multiple organ systems.[1] The pharmacotherapy of systemic autoimmune disorders is rather challenging due to chronic treatment regimens and a higher disease relapse rate.[2] The complex drug regimen is associated with a high risk of drug-related problems (DRPs).[3] As DRPs are becoming one of the major concerns in modern clinical practice, timely identification and their resolution are critical in lowering the therapeutic related harm. Patient satisfaction can be enhanced through drug therapy optimization, reducing economic and iatrogenic burdens.[4]
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