乌干达儿科传染病诊所二线方案HIV青少年的营养状况及其相关因素

IF 0.4 Q4 SOCIAL WORK Journal of HIV-AIDS & Social Services Pub Date : 2022-01-01 DOI:10.1080/15381501.2021.2015503
D. Dave, Ainembabazi Provia, N. Nakiddu, Erin Sodawasser, Katrina Harper, J. Ssenkusu, S. Kitaka, M. Nicol, J. Musaazi, C. Sekaggya
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引用次数: 0

摘要

摘要:我们进行了一项横断面研究,描述了在儿科传染病诊所(PIDC)接受阿扎那韦治疗的HIV阳性青少年的营养状况,其中包括132名青少年。营养不良被定义为二元复合结果(消瘦或发育不良):28%的人营养不良,7.25%的人消瘦,25%的人发育不良。没有父母的青少年更容易营养不良(APR: 2.50, 95% CI: 1.15-5.39, p值= 0.020)。至少接受过中等教育的青少年营养不良的可能性较小(APR: 0.54, CI: 0.32-0.92, p值= 0.024)。与其他研究相比,在艾滋病毒阳性青少年中观察到的营养不良患病率较低。然而,对于一个城市中心来说,这一比例仍然很高,这与在抗逆转录病毒治疗可及性提高的时代,耐药性不断上升有关。这就要求提供更多的支持和适当的干预措施,进一步优化接受艾滋病毒治疗的青少年的营养护理,以减轻对二线治疗方案的耐药性上升。
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Nutritional status and its associated factors among HIV adolescents on second line regimen at Pediatric Infectious Diseases Clinic in Uganda
Abstract We performed a cross-sectional study to describe the nutritional status among HIV positive adolescents on Atazanavir-based regimen attending Pediatric Infectious Diseases Clinic (PIDC), in which 132 adolescents were included. Undernutrition was defined as a binary composite outcome (thinness or stunting): 28% were undernourished, 7.25% were thin, and 25% were stunted. Adolescents with no parent were more likely to be undernourished (APR: 2.50, 95% CI: 1.15–5.39, p-value = .020). Adolescents who had attained at least secondary education were less likely to be undernourished (APR: 0.54, CI:0.32–0.92, p-value = .024). Prevalence of undernutrition observed among HIV positive adolescents was lower compared to other studies. However, this is still high for an urban center, and this is concerning with increasing rates of drug resistance in an era of increased ART accessibility. This calls for more support and appropriate interventions for further optimizing nutrition care among adolescents on HIV treatment to mitigate the rise of resistance to second line regimens.
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