一例罕见的肾上腺素能性心肌炎并发心源性休克的处理

L. Macovei, R. Magopet, L. Anghel, M. Balasanian, C. Răileanu, D. Marcu, C. Prisăcariu, C. Stătescu
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引用次数: 0

摘要

一位41岁的女性因进行性呼吸困难和晕厥而被转介到我们的诊所,之前有心绞痛。入院时她有心源性休克。心电图显示弥漫性复极改变,心肌酶升高。超声心动图显示严重的左心室功能不全,伴有基底壁和中壁运动障碍。稳定病情后,行冠状动脉造影,显示心外膜动脉正常。在接下来的几天里,她的临床状况表现为严重的高血压发作,并伴有肺水肿和对治疗的低反应。心血管磁共振显示心肌水肿和心肌内晚期钆增强。腹部超声提示怀疑嗜铬细胞瘤,因为在右侧肾上腺发现异常肿块伴囊性区。尿游离儿茶酚胺和分离肾上腺素升高证实了诊断。进一步,CT扫描更好地识别了异质性肿瘤,患者被转介进行右侧腹腔镜肾上腺切除术。随访1个月,收缩压功能完全恢复。本病例的特殊性表现在肾上腺素能性心肌炎的诊断困难,以及由此引起的心源性休克的处理困难。
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Management of a rare case of adrenergic myocarditis complicated with cardiogenic shock
A 41-year-old female was referred to our clinic with progressive dyspnea and a syncope, preceded by angina. On admission she was in cardiogenic shock. ECG showed diffuse repolarization changes and cardiac enzymes were elevated. The echocardiogram revealed severe left ventricular dysfunction with basal and medium walls hypokinesia. After stabilizing the patient, a coronary angiography was performed which revealed normal epicardial arteries. In the next days her clinical status was marked by severe hypertensive episodes with flash pulmonary edema and low responsiveness to therapy. Cardiovascular magnetic resonance showed myocardial edema and intramyocardial late gadolinium enhancement. An abdominal ultrasound raised suspicion of a pheochromocytoma due to an abnormal mass with cystic areas found on the right suprarenal gland. Elevated urinary free catecholamines and fractionated metanephrines confirmed the diagnosis. Further on, a CT scan better identified the heterogeneous tumor and the patient was referred for a right laparoscopic adrenalectomy. Follow-up at 1 month reported full recovery of the sistolic function. The particularity of the case is represented by the difficulty of diagnosis of adrenergic myocarditis, as well as the management of cardiogenic shock induced by it.
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