印度人群类风湿关节炎患病率和DMARDs使用:一项横断面研究

IF 0.4 Q4 PHARMACOLOGY & PHARMACY Asian Journal of Pharmaceutics Pub Date : 2021-06-01 DOI:10.22377/ajp.v15i3.4148
T. Goud
{"title":"印度人群类风湿关节炎患病率和DMARDs使用:一项横断面研究","authors":"T. Goud","doi":"10.22377/ajp.v15i3.4148","DOIUrl":null,"url":null,"abstract":"Background: Rheumatoid arthritis (RA) is an autoimmune disorder characterized by symmetric and erosive synovitis with extra-articular involvement in some cases. RA prevalence in India is 0.75%. The study is to estimate the prevalence of RA in the South Indian population and to determine the demographic characteristics such as gender, age, geographical locality, and usage of antirheumatic drugs. Methodology: This prospective cross-sectional study was conducted in 600 patients of both male and female at advance rheumatology center. The patients were selected based on inclusion and exclusion criteria. Patients who are suspected and diagnosed newly with RA, patients who are already with RA attending the rheumatoid center and are on therapy, and patients age equal to and above 16 years either gender are included in the study. Patients with other arthritic and immunologic problems such as osteoarthritis, psoriatic arthritis, systemic lupus erythematosus, spondylosis, and osteoporosis were excluded from the study and patient’s age below 16 years are excluded from the study. Results: Among 600 patients presented to advance rheumatology center, 174 patients are identified with classical symptoms of RA, in those female and male patients are 132 and 42, respectively. The mean age of total patients is 45.51 ± 12.09. The estimated prevalence was found to be 0.29 or 29% (95% confidence interval is 0.25–0.33). Disease-modifying antirheumatic drugs (36.9%) are mostly prescribed. Conclusion: This study witnessed a rise in the prevalence of RA in South Indian population which gives alarming signals to the health authority and policymakers to increase the awareness on RA in India.","PeriodicalId":8489,"journal":{"name":"Asian Journal of Pharmaceutics","volume":null,"pages":null},"PeriodicalIF":0.4000,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prevalence of Rheumatoid Arthritis and DMARDs Usage in Indian Population: A Cross-Sectional Study\",\"authors\":\"T. Goud\",\"doi\":\"10.22377/ajp.v15i3.4148\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Rheumatoid arthritis (RA) is an autoimmune disorder characterized by symmetric and erosive synovitis with extra-articular involvement in some cases. RA prevalence in India is 0.75%. The study is to estimate the prevalence of RA in the South Indian population and to determine the demographic characteristics such as gender, age, geographical locality, and usage of antirheumatic drugs. Methodology: This prospective cross-sectional study was conducted in 600 patients of both male and female at advance rheumatology center. The patients were selected based on inclusion and exclusion criteria. Patients who are suspected and diagnosed newly with RA, patients who are already with RA attending the rheumatoid center and are on therapy, and patients age equal to and above 16 years either gender are included in the study. Patients with other arthritic and immunologic problems such as osteoarthritis, psoriatic arthritis, systemic lupus erythematosus, spondylosis, and osteoporosis were excluded from the study and patient’s age below 16 years are excluded from the study. Results: Among 600 patients presented to advance rheumatology center, 174 patients are identified with classical symptoms of RA, in those female and male patients are 132 and 42, respectively. The mean age of total patients is 45.51 ± 12.09. The estimated prevalence was found to be 0.29 or 29% (95% confidence interval is 0.25–0.33). Disease-modifying antirheumatic drugs (36.9%) are mostly prescribed. Conclusion: This study witnessed a rise in the prevalence of RA in South Indian population which gives alarming signals to the health authority and policymakers to increase the awareness on RA in India.\",\"PeriodicalId\":8489,\"journal\":{\"name\":\"Asian Journal of Pharmaceutics\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2021-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Asian Journal of Pharmaceutics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22377/ajp.v15i3.4148\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian Journal of Pharmaceutics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22377/ajp.v15i3.4148","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0

摘要

背景:类风湿性关节炎(RA)是一种自身免疫性疾病,其特征是对称性和糜烂性滑膜炎,在某些情况下累及关节外。RA在印度的患病率为0.75%。该研究旨在估计南印度人群中RA的患病率,并确定其人口统计学特征,如性别、年龄、地理位置和抗风湿药物的使用情况。方法:这项前瞻性横断面研究在600名男性和女性患者中进行。根据纳入和排除标准选择患者。怀疑和新诊断为类风湿性关节炎的患者,已经患有类风湿性关节炎并在类风湿中心接受治疗的患者,以及年龄在16岁及以上的患者,无论男女,都包括在研究中。患有其他关节炎和免疫问题(如骨关节炎、银屑病关节炎、系统性红斑狼疮、颈椎病和骨质疏松症)的患者被排除在研究之外,年龄在16岁以下的患者被排除在研究之外。结果:600例就诊于advance风湿病中心的患者中,有174例确诊为典型RA症状,其中女性132例,男性42例。患者平均年龄45.51±12.09岁。估计患病率为0.29或29%(95%可信区间为0.25-0.33)。治疗疾病的抗风湿药物(36.9%)多为处方药。结论:本研究表明,南印度人群中RA患病率的上升给卫生当局和政策制定者敲响了警钟,以提高对RA在印度的认识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Prevalence of Rheumatoid Arthritis and DMARDs Usage in Indian Population: A Cross-Sectional Study
Background: Rheumatoid arthritis (RA) is an autoimmune disorder characterized by symmetric and erosive synovitis with extra-articular involvement in some cases. RA prevalence in India is 0.75%. The study is to estimate the prevalence of RA in the South Indian population and to determine the demographic characteristics such as gender, age, geographical locality, and usage of antirheumatic drugs. Methodology: This prospective cross-sectional study was conducted in 600 patients of both male and female at advance rheumatology center. The patients were selected based on inclusion and exclusion criteria. Patients who are suspected and diagnosed newly with RA, patients who are already with RA attending the rheumatoid center and are on therapy, and patients age equal to and above 16 years either gender are included in the study. Patients with other arthritic and immunologic problems such as osteoarthritis, psoriatic arthritis, systemic lupus erythematosus, spondylosis, and osteoporosis were excluded from the study and patient’s age below 16 years are excluded from the study. Results: Among 600 patients presented to advance rheumatology center, 174 patients are identified with classical symptoms of RA, in those female and male patients are 132 and 42, respectively. The mean age of total patients is 45.51 ± 12.09. The estimated prevalence was found to be 0.29 or 29% (95% confidence interval is 0.25–0.33). Disease-modifying antirheumatic drugs (36.9%) are mostly prescribed. Conclusion: This study witnessed a rise in the prevalence of RA in South Indian population which gives alarming signals to the health authority and policymakers to increase the awareness on RA in India.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Asian Journal of  Pharmaceutics
Asian Journal of Pharmaceutics PHARMACOLOGY & PHARMACY-
自引率
0.00%
发文量
47
期刊介绍: Character of the publications: -Pharmaceutics and Pharmaceutical Technology -Formulation Design and Development -Drug Discovery and Development Interface -Manufacturing Science and Engineering -Pharmacokinetics, Pharmacodynamics, and Drug Metabolism -Clinical Pharmacology, General Medicine and Translational Research -Physical Pharmacy and Biopharmaceutics -Novel Drug delivery system -Biotechnology & Microbiological evaluations -Regulatory Sciences
期刊最新文献
A Design of Experiment-based Approach for the Formulation Development and Evaluation of Repaglinide Transdermal Patch Using Natural Polymers Modification of Human Behavior due to Coronavirus Outbreak: A Brief Study on Current Scenario Formulation and Evaluation of Sustained Release Bilayer Tablets of Losartan Potassium Bioanalytical Method Development and Validation of Empagliflozin by LC–MS/MS Method and Quantitative Estimation of Drug Concentration in Human Plasma Formulation and Evaluation of Antidiabetic Polyherbal Tablets
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1