{"title":"田口设计聚乙烯醇(PVA)/阿拉伯胶(AG)/MgO纳米颗粒生物纳米复合材料漱口水抗菌性能研究","authors":"Mohammad Salmani Mobarakeh, A. Moghadam","doi":"10.1680/jbibn.21.00035","DOIUrl":null,"url":null,"abstract":"Untreated dental caries is an important word challenge in human life. In this work, we synthesized polyvinyl alcohol-gum arabic-magnesium oxide nanoparticles new bionanocomposite and evaluated the antibacterial properties of its against Streptococcus mutans biofilm in vitro. For optimization of variables to have the maximum antibacterial property, L9 orthogonal array of Taguchi method was used for design of extraction conditions. The nanocomposites were characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), X-ray energy diffraction (EDS), Thermogravimetric analysis (TGA) and transmission electron microscopy (TEM) tests. The FESEM images of nanocomposite inhibit that the nanoparticles are entirely surrounded with polymers chains of matrix and nanoparticles are deposited on the its walls, thus a layered nanocomposite is formed. The sheet width and size range of the nanocomposite was determined between 30-40 and 20-90 nm, respectively. The results showed that the synthesized nanocomposite with conditions of 1 mg/ml PVA, 3 mg/ml AG, and 6 mg/ml MgO (experiment 3), had the strongest antibacterial activity against the Streptococcus mutans bacteria’s biofilm. In this condition, the bacterial survival rate was the lowest at 0.21 CFU/ml and under this optimal conditions could inhibit the activity of Streptococcus mutans bacteria at a rate of 0.09 CFU/ml.","PeriodicalId":48847,"journal":{"name":"Bioinspired Biomimetic and Nanobiomaterials","volume":" ","pages":""},"PeriodicalIF":1.3000,"publicationDate":"2022-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Investigation of antibacterial activity of new bionanocomposite based on polyvinyl alcohol(PVA)/arabic gum(AG)/MgO nanoparticles by Taguchi design for mouthwash application\",\"authors\":\"Mohammad Salmani Mobarakeh, A. Moghadam\",\"doi\":\"10.1680/jbibn.21.00035\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Untreated dental caries is an important word challenge in human life. In this work, we synthesized polyvinyl alcohol-gum arabic-magnesium oxide nanoparticles new bionanocomposite and evaluated the antibacterial properties of its against Streptococcus mutans biofilm in vitro. For optimization of variables to have the maximum antibacterial property, L9 orthogonal array of Taguchi method was used for design of extraction conditions. The nanocomposites were characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), X-ray energy diffraction (EDS), Thermogravimetric analysis (TGA) and transmission electron microscopy (TEM) tests. The FESEM images of nanocomposite inhibit that the nanoparticles are entirely surrounded with polymers chains of matrix and nanoparticles are deposited on the its walls, thus a layered nanocomposite is formed. The sheet width and size range of the nanocomposite was determined between 30-40 and 20-90 nm, respectively. The results showed that the synthesized nanocomposite with conditions of 1 mg/ml PVA, 3 mg/ml AG, and 6 mg/ml MgO (experiment 3), had the strongest antibacterial activity against the Streptococcus mutans bacteria’s biofilm. In this condition, the bacterial survival rate was the lowest at 0.21 CFU/ml and under this optimal conditions could inhibit the activity of Streptococcus mutans bacteria at a rate of 0.09 CFU/ml.\",\"PeriodicalId\":48847,\"journal\":{\"name\":\"Bioinspired Biomimetic and Nanobiomaterials\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2022-08-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bioinspired Biomimetic and Nanobiomaterials\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1680/jbibn.21.00035\",\"RegionNum\":4,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioinspired Biomimetic and Nanobiomaterials","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1680/jbibn.21.00035","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
Investigation of antibacterial activity of new bionanocomposite based on polyvinyl alcohol(PVA)/arabic gum(AG)/MgO nanoparticles by Taguchi design for mouthwash application
Untreated dental caries is an important word challenge in human life. In this work, we synthesized polyvinyl alcohol-gum arabic-magnesium oxide nanoparticles new bionanocomposite and evaluated the antibacterial properties of its against Streptococcus mutans biofilm in vitro. For optimization of variables to have the maximum antibacterial property, L9 orthogonal array of Taguchi method was used for design of extraction conditions. The nanocomposites were characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), X-ray energy diffraction (EDS), Thermogravimetric analysis (TGA) and transmission electron microscopy (TEM) tests. The FESEM images of nanocomposite inhibit that the nanoparticles are entirely surrounded with polymers chains of matrix and nanoparticles are deposited on the its walls, thus a layered nanocomposite is formed. The sheet width and size range of the nanocomposite was determined between 30-40 and 20-90 nm, respectively. The results showed that the synthesized nanocomposite with conditions of 1 mg/ml PVA, 3 mg/ml AG, and 6 mg/ml MgO (experiment 3), had the strongest antibacterial activity against the Streptococcus mutans bacteria’s biofilm. In this condition, the bacterial survival rate was the lowest at 0.21 CFU/ml and under this optimal conditions could inhibit the activity of Streptococcus mutans bacteria at a rate of 0.09 CFU/ml.
期刊介绍:
Bioinspired, biomimetic and nanobiomaterials are emerging as the most promising area of research within the area of biological materials science and engineering. The technological significance of this area is immense for applications as diverse as tissue engineering and drug delivery biosystems to biomimicked sensors and optical devices.
Bioinspired, Biomimetic and Nanobiomaterials provides a unique scholarly forum for discussion and reporting of structure sensitive functional properties of nature inspired materials.