微波辅助水介质中C-C和C-杂原子键的形成

IF 0.9 Q4 CHEMISTRY, MULTIDISCIPLINARY Current Microwave Chemistry Pub Date : 2021-08-23 DOI:10.2174/2213335608666210823093626
Bijeta Mitra, P. Ghosh
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引用次数: 0

摘要

近年来,微波辅助化学在有机合成中获得了巨大的吸引力,因为它具有避免苛刻反应条件、提高产率、消除副产物、缩短反应时间和消除浪费等多方面优点。此外,水作为反应介质还包括更多的好处,因为它消除了有毒溶剂的所有缺点,这些缺点可能会对我们的地球母亲造成伤害。此外,C-C和C-杂原子键的形成反应是非常重要的,因为大多数药物以及生物活性化合物都含有杂环或C-杂键,这是化学的关键工具。本文介绍了微波辅助水介质中C-C和C-杂原子键形成反应的研究进展。
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Microwave-assisted C-C and C-heteroatom bond formations in aqueous medium
In recent times, microwave assisted chemistry have gained enormous attraction in organic synthesis owing to its versatile advantages such as avoidance of harsh reaction condition, increase of yield, eliminates of by product, shorter reaction time and removal of wastages. Besides, water as a reaction medium further includes more benefit as it eliminates all the drawbacks of toxic solvent which may cause injuries for our mother earth. Furthermore C-C and C-heteroatom bond formation reactions are very significant as most of the drug as well as bioactive compounds contain heterocycles or C-hetero bond which is a key tool of chemistry. This article demonstrates the advancement on the topic of the microwave assisted C-C and C-heteroatom bond formation reactions in aqueous medium.
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来源期刊
Current Microwave Chemistry
Current Microwave Chemistry CHEMISTRY, MULTIDISCIPLINARY-
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