用蒙特卡罗模拟的电子治疗监测单元计算:用于相空间场修剪的GUI

T. Sivayogan, J. Chow
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引用次数: 0

摘要

目的:我们利用蒙特卡罗模拟开发了一个电子相空间场修剪的图形用户界面(GUI)。该图形用户界面可用于电子治疗中监测单元(MU)的计算。方法:利用MATLAB和C语言编写图形用户界面和电子场裁剪算法。使用EGSnrc代码生成电子场的相空间文件,该代码基于瓦里安21EX直线加速器,具有施加器尺寸、场大小和能量等变量。通过比较用于MU计算的相对输出因子、蒙特卡罗模拟预测的相对输出因子和实际测量的相对输出因子,对算法进行了验证。结果:我们的电子场修剪算法比原来的蒙特卡罗模拟快5倍左右。临床上,当体素尺寸≥0.3 × 0.3 × 0.3 cm3,视场半径大于2cm时,GUI表现最佳,可接受偏差为2%。结论:建立了一个基于蒙特卡罗模拟生成不规则场的图形用户界面,为电子治疗提供了一个友好的工具。
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Monitor unit calculation in electron therapy using Monte Carlo Simulation: a GUI for the phase-space field trimming
Purpose: We developed a graphical user interface (GUI) for electron phase-space field trimming using Monte Carlo simulations. This GUI can be used for monitor unit (MU) calculation in electron therapy. Methods: The GUI and electron field trimming algorithm were developed using MATLAB and C code. Phase-space files for the electron fields were generated using the EGSnrc code based on a Varian 21EX Linac with variables of applicator size, field size and energy. Verification of the alogrithm was carried out by comparing the relative output factor, which was used for MU calculation, predicted by Monte Carlo simulations and from actual measurements. Results: Our electron field trimming algorithm was found to be about five times faster than the original Monte Carlo simulation. Clinically, the GUI performed best when using voxel size ≥ 0.3 × 0.3 × 0.3 cm3, and field size larger than 2 cm in radius based on an acceptable deviation of 2%. Conclusion: A GUI for generating irregular field for MU calculation using Monte Carlo simulations was created as a user-friendly tool in electron therapy.
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