基于停止-开始标准的内科及神经内科重症监护病房65岁及以上患者不当用药发生率评估

IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL Gazi Medical Journal Pub Date : 2023-07-01 DOI:10.12996/gmj.2023.62
Özdağ Erdil, H. Z. Güney
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引用次数: 0

摘要

引言:身体中许多系统都会出现与衰老有关的生理变化。需要对老年人群的治疗方式和药物处方过程进行重新评估。为了详细说明多药治疗,还必须有效地确定个人应使用的药物数量。为老年人开处方和使用药物制定了各种标准。这些标准中使用最多的被称为Beers标准。STOPP和START标准是使用的其他标准。材料和方法:我们的研究旨在根据STOP-START标准,回顾性评估在安卡拉阿塔图克训练研究医院内科和神经重症监护室住院的65岁及以上患者中不适当药物使用的患病率。结果:研究组包括168名(58.3%)女性和120名(41.7%)男性。288名患者共诊断出727种疾病。其中201项为“脑血管疾病”,153项为“高血压”而最常见的STOPP标准主要组和单一标准分别是抗血小板抗凝剂组(35,7%)、“存在导致重复的药物类别(在添加新药物之前用单一药物达到最佳水平)”(23,2%)。同时,最常见的START标准主要组和单一标准分别是心血管系统组(94.5%)和“对接近生命终点或年龄不超过85岁、有冠状动脉、脑血管或外周血管病史的患者进行他汀类药物治疗”(70.2%)。结论:研究结果与国内文献基本一致。研究结果与国际文献之间存在党派差异。预计这些差异可归因于所使用的诊断标准、研究组选择和研究设计的差异。
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The Evaluation of the Prevalence of Improper Medication Use in Patients Age of 65 and over in Internal Diseases and Neurology Intensive Care Units in Terms of Stopp-Start Criteria
Introduction: Physiological changes are seen in many systems in the body related to aging. Treatment modalities and drug prescribing processes need to be re-evaluated in the geriatric population. To elaborate on polypharmacy, the number of drugs the individual should use must also be defined effectively. Various criteria have been developed for prescribing and using drugs for elderly individuals. The most used of these criteria is called the Beers criteria. STOPP and START criteria are other criteria used. Material and Method: Our study aimed to retrospectively evaluate the prevalence of inappropriate drug use in patients aged 65 and over who were hospitalized in the Internal Medicine and Neurology Intensive Care Units of Ankara Atatürk Training and Research Hospital in terms of STOPP-START criteria. Results: Study group consists of 168 (58,3%) female and 120 (41,7%) male. A total of 727 diseases were diagnosed in 288 patients. 201 of these were "Cerebrovascular Diseases,” 153 were "Hypertension.” While the most common STOPP criterion main group and single criterion were antiplatelet anticoagulant agent group (35,7%), “Presence of a drug class causing duplication (Aiming optimum level with a single drug before adding a new agent) (23,2%)”, respectively. At the same time, the most common START criterion main group and single criterion were cardiovascular system group (94,5%), and “Statin therapy in patients who are near the end of life or who are not older than 85 years of age, with a history of coronary, cerebral or peripheral vascular disease”, respectively (70,2%). Conclusion: It is seen that the study results are generally similar to the national literature. There are partisan differences between the study results and the international literature. It is anticipated that these differences can be attributed to the diagnostic criteria used, study group selection, and study design differences.
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来源期刊
Gazi Medical Journal
Gazi Medical Journal MEDICINE, GENERAL & INTERNAL-
CiteScore
0.30
自引率
0.00%
发文量
105
审稿时长
16 weeks
期刊介绍: Gazi Medical Journal is being published from 1990 four times annually. Gazi Medical Journal is an international journal presenting research results in all medical fields, with the aim of becoming the premier source of high quality research from Eastern Europe , Middle East and Asia. The Gazi Medical Journal is peer-reviewed and is published quarterly in paper and electronic version. The language of the Gazi Medical Journal is English and Turkish. Offerings include research articles, rapid communications, case reports, letters to the editor, meta-analyses and commentaries
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