射线诱导聚合法制得纳米凝胶

IF 1.1 4区工程技术 Q4 POLYMER SCIENCE Polimery Pub Date : 2021-10-29 DOI:10.14314/polimery.2021.9.1

Nurul Amirah Shafie, M. Hamzah, R. R. Ali

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引用次数: 1

摘要

研究了甲基丙烯酸2-（二甲氨基）乙酯（DMAEMA）浓度对γ辐射聚合N-异丙基丙烯酰胺（NIPAAM）、聚乙烯吡咯烷酮（PVP）、聚乙二醇二丙烯酸酯（PEGDA）纳米凝胶温度敏感性的影响。动态光散射（DLS）和ζ电位测量用于表征纳米凝胶。研究发现，温度会导致纳米凝胶颗粒膨胀和收缩，从而可以控制胶囊中药物的剂量。所开发的纳米凝胶是一种极具生物医学应用潜力的材料。

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Nanogels obtained by gamma radiation induced polymerization

The influence of 2-(dimethylamino)ethyl methacrylate (DMAEMA) concentration on the temperature sensitivity of nanogels based on N-isopropylacrylamide (NIPAAM), poly(vinylpyrrolidone) (PVP), poly(ethylene glycol) diacrylate (PEGDA) by gamma radiation induced polymerization was investigated. Dynamic light scattering (DLS) and zeta potential measurements were used to characterize the nanogels. Temperature has been found to cause the nanogel particles to swell and shirnkage, allowing controlled dosing of the drug contained in capsules. The developed nanogels are promising materials with great potential for biomedical applications.

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来源期刊

Polimery Materials Science-Polymers and Plastics

CiteScore

2.90

自引率

6.20%

发文量

审稿时长

1 months

期刊介绍： The "Polimery" journal, of international circulation, is publishing peerreviewed scientific and technical research papers covering polymer science and technology in the field of polymers, rubbers, chemical fibres and paints. The range of topics covered are raw materials, polymer synthesis, processing and applications of polymers. Apart from scientific and technical research papers the monthly includes technical and commercial information such as reports from fairs and exhibitions as well as home, world and technical news. “Polimery "- an international journal covering the following topics: polymers, rubber, chemical fibres and paints. The Journal is addressed to scientists, managers and engineering staff of universities, Polish Academy of Sciences, R&D institutions, industry, specializing in polymer chemistry, physical chemistry, technology and processing. “Polimery” publishes original, reviewed research, scientific and technology papers in the field of polymer synthesis, analysis, technology and modification, processing, properties, applications and recycling.