蚯蚓作为周围神经再生的生物材料:综述

Q3 Health Professions Traditional and Integrative Medicine Pub Date : 2023-04-08 DOI:10.18502/tim.v8i1.12405
Saeed Ebrahimi Fana, Fathollah Ahmadpour, H. Rasouli, M. Maniati
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引用次数: 1

摘要

迄今为止,许多与蚯蚓相关的作用已被介绍,包括伤口愈合作用以及抗微生物、抗炎和抗血栓形成作用。EW生物材料也可以作为治疗各种神经炎症的药物。此外,土著居民传统上从EW中提取药用化合物。因此,本研究旨在探讨电刺激对神经再生的影响。利用PubMed、Scopus、Web of Science和b谷歌等数据库进行了详尽的文献检索。共纳入13项研究。所有这些研究都包括动物模型或2009年至2018年间的细胞培养研究。对这些发现的描述见表1。尽管出版物数量有限,结果也存在争议,但考虑到有几项证据证实EW生物材料对神经损伤和再生的影响,EW可以被视为神经修复的一种新的有希望的选择。
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Earthworm as a Peripheral Nerve Regeneration Biomaterial: A Comprehensive Review
Many Earthworm (EW) related effects have been introduced so far including, wound healing effects as well as anti-microbial, anti-inflammatory and anti-thrombosis effects. EW biomaterials could also be a therapeutic agent for various neuroinflammatory conditions. Besides, indigenous people traditionally have practiced the extraction of medicinal compounds from EW. Therefore, the present study aimed to investigate the EW capacities in nerve regeneration. An exhaustive literature search was performed using databases including PubMed, Scopus, Web of Science and Google. A total of 13 studies were included. All of them included an animal model or were cell culture studies between 2009 and 2018. The description of these findings is given in table 1. Despite the limited number of publications and their controversial results, EW can be regarded as a new promising option for nerve repair, given the several pieces of evidence confirming the effects of EW biomaterials on nerve injury and regeneration.
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来源期刊
Traditional and Integrative Medicine
Traditional and Integrative Medicine Health Professions-Complementary and Manual Therapy
CiteScore
1.10
自引率
0.00%
发文量
48
审稿时长
12 weeks
期刊最新文献
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