维生素D缺乏在贝尔氏麻痹发病及预后中的作用

IF 0.2 Q4 OTORHINOLARYNGOLOGY ENT Updates Pub Date : 2020-12-17 DOI:10.32448/entupdates.814569
E. Ocak, M. Uyar, Deniz Kocaöz, Emre Mirici, A. Acar
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引用次数: 1

摘要

目的:探讨维生素D在贝尔氏麻痹(BP)病因及预后中的作用。方法:以诊断为BP的患者和健康志愿者为对照组,进行前瞻性对照临床研究。测量了所有受试者体内的维生素D水平。在同质组中,根据参与者的House-Brackmann (HB)分级评估维生素D对病因和预后的影响。结果:BP组和对照组的维生素D水平相似。在BP组中,晚期HB患者的维生素D水平较低。此外,无论初始HB分级如何,维生素D含量<10ng/ml的患者预后较差(p=0.01)。结论:我们的研究结果表明维生素D水平可能对BP的预后有影响。较低的维生素D水平可能会对康复产生负面影响,特别是对晚期患者。
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Role of Vitamin D Deficiency on The Onset and Prognosis of Bell’s Palsy
Objective: To investigate the role of vitamin D on the etiology and the prognosis of Bell’s Palsy (BP). Methods: A prospective controlled clinical study was conducted on patients diagnosed as BP and healthy volunteers as control group. Vitamin D levels were measured in all subjects. In a homogenous group, effects of vitamin D on the etiology and prognosis were evaluated according to House-Brackmann (HB) grades of participants. Results: Vitamin D levels were similar in the BP and control groups. In BP group, patients with advanced HB grades had lower vitamin D levels. Moreover poorer outcomes (p=0.01) were achieved in patients who had <10ng/ml vitamin D, regardless the initial HB grade. Conclusion: Our results demonstrated a possible role of vitamin D levels on the prognosis of BP. Lower vitamin D levels may have a negative effect on recovery particularly in patients with advanced grades.
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ENT Updates
ENT Updates OTORHINOLARYNGOLOGY-
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