羟基磷灰石作为聚合物填料的生物医学应用综述

Alhussein Arkan Majhooll, I. Zainol, C. Jaafar, H. Alsailawi, M. Hassan, Mustafa Mudhafar, Ali Arkan Majhool, Abbas Asaad
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引用次数: 8

摘要

通过天然来源(如鱼鳞或化学反应产生的合成HA)制备羟基磷灰石(HA)已被广泛用作生物医学材料,因为HA具有生物活性、无毒性和骨传导性,其晶体结构几乎与骨矿物相似。此外,粒径<10微米的HA被归类为常用的无机填料,用于改善聚合物复合材料的机械性能和生物相容性。本综述的目的是收集与羟基磷灰石相关的信息,并为读者提供有关羟基磷灰石作为生物材料的合成方法、优点以及聚合物/HA复合材料的生物医学应用的信息。
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A Brief Review on Biomedical Applications of Hydroxyapatite Use as Fillers in Polymer
Preparation of hydroxyapatite (HA) through natural sources, such as fish scales or synthetic HA produced from the chemical reaction has been widely used as biomedical materials because HA is bioactive, non-toxic and osteoconductive with a crystallographic structure almost similar to that of the bone mineral. In addition, HAwith particle size < 10 microns is classified as common inorganic filler used to improve the mechanical properties and biocompatibility of polymer composites. The purpose of this review is to collect information related to HA, and to provide readers with information about synthesis methods, advantages of hydroxyapatite as biomaterial,biomedical applications of polymer/HA composites.
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