微纳米机器人辅助靶向药物递送,癌症治疗的手术和放疗

Raj Bhusan Singh, Sudhanshu Mishra, Smriti Ojha, A. Shukla, Hina Chaddha
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引用次数: 0

摘要

癌症是指进行性异常细胞生长,有可能侵入或扩散到身体其他部位。许多癌症疗法继续以全身化疗和放射治疗为基础。已经开发了许多纳米医学策略来解决这些疗法的非靶向性及其可能引起的严重副作用。由于靶向治疗仍然很困难,工程机器人和微型机器人越来越受到关注和应用。微型机器人由于其独特的特征和功能,如运动性,可以穿透恶性组织,因此可以更有效地到达恶性肿瘤。建立在信息技术基础上的现代癌症治疗技术可以提高患者的依从性并提高患者的生存率。脆弱的组织可能会被辐射和手术过度损伤,大多数化疗药物无法穿透血脑屏障到达肿瘤。癌症的预防、早期发现、快速诊断和及时治疗至关重要。机器人技术应用于各种医疗环境,其在外科手术中的应用也在不断发展,对癌症治疗领域产生了影响。在机器人的帮助下,癌症治疗的一个关键改进是能够直接靶向肿瘤并将药物输送给肿瘤。
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Micro and Nano Robotics-assisted Targeted Drug Delivery, Surgery and Radiotherapy for Cancer Treatment
Cancer refers to the progressive abnormal cell growth with the potential to invade or spread to other parts of the body. Many cancer therapies continue to be based on systemic chemotherapy along with radiation therapy. Numerous nanomedicine strategies have been developed to address the untargeted nature of these therapies and the serious side effects they can cause. As targeted therapeutic delivery is still difficult, engineered robots and microrobots are getting more and more attention and applicability. Microrobots can more effectively reach malignancies because of their unique features and functions, like their motility, which allows them to penetrate malignant tissues. Modern cancer treatment techniques built on information technology can boost patient compliance and improve patient survival. The delicate tissue can be overly damaged by radiation and surgery, and most chemotherapy medications are unable to penetrate the blood-brain barrier and reach the tumor. Cancer prevention, its early detection, quick diagnosis, and prompt treatment are very crucial. Robotic technology is employed in a variety of medical settings, and its applications in surgery have evolved that have an impact on the field of cancer treatment as well. A key improvement in cancer therapy with the aid of robotics would be the ability to target and deliver medications directly to the tumor.
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来源期刊
CiteScore
1.00
自引率
0.00%
发文量
50
期刊介绍: Current Cancer Therapy Reviews publishes frontier reviews on all the latest advances in clinical oncology, cancer therapy and pharmacology. The journal"s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians in cancer therapy.
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