确定印度糖尿病前期和心血管疾病与代谢综合征患者的关系

Ivon Lewis, Shimpa R. Sharma, Prashanthkumar Goudappala, A. Joshi
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引用次数: 0

摘要

背景:在印度等发展中国家,城市化程度的提高减少了人们的身体活动,从而导致人们患上许多危及生命的疾病。代谢综合征增加了中年人的健康负担和死亡率。早期诊断与这种病理障碍相关的危险因素可以通过延缓疾病进展来帮助克服这种危及生命的病理障碍。材料与方法:共筛选400例代谢综合征患者。采集并处理患者血液样本。生化参数包括空腹血糖和脂质谱,包括TC、HDL、LDL -极低密度脂蛋白(VLDL)和甘油三酯,使用自动分析仪进行分析。改变空腹血糖水平和血脂被用来诊断糖尿病和心血管疾病的状态。结果:本组患者空腹血糖处于糖尿病前期水平,糖尿病发病率较高。血脂比例的改变与好胆固醇水平的降低和坏胆固醇水平的增加也被观察到与糖尿病前期状况有关。结论:代谢综合征患者中这些生化参数水平的改变说明了印度人群中前驱糖尿病与心血管疾病之间的关系。
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Identifying the Association of Prediabetes and Cardiovascular Diseases with Metabolic Syndrome Patients in India
Background: Increased urbanization decreases physical activity which promotes many life-threatening diseases among people in developing countries like India. Metabolic syndrome increases the health burden and mortality rate among middle-aged people. Early diagnosis of the risk factor associated with this pathological disorder can be a help to overcome this life-threatening pathological disorder by delaying disease progression. Materials and Methods: A total of 400 patients with metabolic syndrome are identified. Patient blood samples were collected and processed. Biochemical parameters include fasting blood sugar and lipid profiles which include TC, HDL, LDL very-LDL (VLDL), and triglycerides were analyzed using an autoanalyzer. Altered fasting blood sugar level and lipid profile are used to diagnose the status of diabetes and cardiovascular disorder. Results: The fasting blood sugar levels of the patients were in the range of prediabetic condition and so the patients are more prevalent to diabetes mellitus. An altered lipid profile ratio with a decreased level of good cholesterol and increased level of bad cholesterol was also observed in association with prediabetic condition. Conclusion: The altered levels of these biochemical parameters in metabolic syndrome patients gives the idea about its association of prediabetes with cardiovascular disorders among the Indian population.
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