分子印迹聚合物:有前途的人类病毒检测工具

IF 0.4 Q4 CHEMISTRY, ANALYTICAL Pakistan Journal of Analytical & Environmental Chemistry Pub Date : 2021-12-23 DOI:10.21743/pjaec/2021.12.01
Muhammad Shahzeb Khan, M. Asif, Amina Khatoon, Shafia Arshad, Shagufta Usman, Iqra Karim
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引用次数: 0

摘要

由于模板取向的活性位点,分子印迹是合成具有高选择性的独特功能聚合物的一个有吸引力的研究领域。分子印迹聚合物(MIPs)由于其机械稳定性、可逆性、再现性和交叉有效性,在化学和生物传感、药物递送和固相萃取方面有着广泛的应用。MIP与天然抗体相容,并且在生物医学领域中被用作抗体模拟物/受体。如今,由于新出现的具有遗传变异性和耐药性的病毒性疾病,病毒检测是最受欢迎的研究领域。因此,有必要通过对病毒病原体的鉴别识别来控制病毒感染。本文综述了利用MIPs检测人类病毒的文献。
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Molecularly Imprinted Polymers: Promising Tool for the Human Virus Detection
Molecular imprinting is an attractive research area for synthesizing unique functional polymers with high selectivity due to template oriented active sites. Molecularly imprinted polymers (MIPs) have a wide range of applications in chemical and biological sensing, drug delivery, and solidphase extraction owing to mechanical stability, reversibility, reproducibility, and cross-validity. MIPs are compatible with natural antibodies and are being used as antibody mimics/receptors in the biomedical field. Today, viral detection is the most popular research area due to emerging viral diseases with genetic variability and drug resistance. Therefore, there is a need to control viral infections by discriminative recognition of the viral pathogens. This review summarizes the literature on the detection of human viruses by using MIPs.
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来源期刊
CiteScore
1.10
自引率
16.70%
发文量
16
审稿时长
15 weeks
期刊最新文献
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