肝移植受者自发性脾肾分流的左肾静脉结扎一例

Q4 Medicine Transplantation Reports Pub Date : 2020-09-01 DOI:10.1016/j.tpr.2020.100053
Jacek Pawlicki, Adam Kurek, Grzegorz Oczkowicz, Robert Król
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引用次数: 1

摘要

对于诊断为肝硬化和门静脉高压症,符合肝移植条件的患者,门静脉系统侧支循环的存在是一种典型的现象。其中一种类型是自发性脾肾分流。大的或多的可引起窃血综合征和移植物灌注不足。试图直接移除这种分流在技术上是困难的,而且充满了并发症。结扎左肾静脉是一种更简单、更安全的方法。本文的目的是提出一个案例,通过左肾静脉结扎确保移植肝的适当灌注,在接受脾肾分流的受者中进行,并回顾了专门用于肝移植受者门系统分流的科学报告。一例63岁女性酒精性肝病患者符合肝移植条件。ct血管造影显示大量脾肾分流,直径达13mm。在肝移植无肝期,观察到门静脉有非常微弱的积液,夹紧左肾静脉后明显改善。结扎肾静脉口,以达到正确的移植物再灌注。术后多普勒超声显示门静脉血流正常。早期肝肾功能良好。最后,在第7个月,由于晚期肝动脉血栓形成导致胆道坏死,患者接受了再次移植手术。结论左肾静脉结扎术可有效预防脾肾分流术后肝移植患者的肾窦性综合征,保证移植物良好的血流灌注。
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Ligation Of The Left Renal Vein In Liver Transplant Recipients Diagnosed With A Spontaneous Splenorenal Shunt – Case Report

Introduction

For patients diagnosed with hepatic cirrhosis and portal hypertension, qualified for liver transplantation, the presence of portosystemic collateral circulation constitutes a typical phenomenon. One of its types is the spontaneous splenorenal shunt. Large or multiple ones may cause the steal syndrome and graft hypoperfusion. An attempt to remove such shunts directly is technically difficult and fraught with complications. An easier and safer method would involve ligating the left renal vein. The aim of this paper is to present a case where proper perfusion of a transplanted liver is ensured by the left renal vein ligation, performed in a recipient with a splenorenal shunt, and to review the scientific reports devoted to portosystemic shunts in liver transplant recipients.

Case report

A 63-year-old female with alcoholic liver disease was qualified for liver transplantation. The CT-angiography showed numerous splenorenal shunts with diameter up to 13 mm. During the anhepatic phase of the liver transplantation a very weak effusion from the portal vein was observed, which improved significantly following clamping of the left renal vein. Thus renal vein orifice was ligated in order to achieve the correct graft reperfusion. Postoperative Doppler ultrasound showed a correct portal blood flow. The early liver and renal function was good. Finally, in the 7th month, the patient underwent a re-transplantation due to biliary necrosis caused by late hepatic artery thrombosis.

Conclusion

Ligation of the left renal vein efficiently prevents the steal syndrome in the liver transplant recipients with splenorenal shunt and ensures good graft perfusion.

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来源期刊
Transplantation Reports
Transplantation Reports Medicine-Transplantation
CiteScore
0.60
自引率
0.00%
发文量
24
审稿时长
101 days
期刊介绍: To provide to national and regional audiences experiences unique to them or confirming of broader concepts originating in large controlled trials. All aspects of organ, tissue and cell transplantation clinically and experimentally. Transplantation Reports will provide in-depth representation of emerging preclinical, impactful and clinical experiences. -Original basic or clinical science articles that represent initial limited experiences as preliminary reports. -Clinical trials of therapies previously well documented in large trials but now tested in limited, special, ethnic or clinically unique patient populations. -Case studies that confirm prior reports but have occurred in patients displaying unique clinical characteristics such as ethnicities or rarely associated co-morbidities. Transplantation Reports offers these benefits: -Fast and fair peer review -Rapid, article-based publication -Unrivalled visibility and exposure for your research -Immediate, free and permanent access to your paper on Science Direct -Immediately citable using the article DOI
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