乙醇对血小板生物学的影响

IF 0.6 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry Pub Date : 2022-11-16 DOI:10.1134/S1990750822040023
M. I. Airapetov, S. O. Eresko, E. R. Bychkov, A. A. Lebedev, P. D. Shabanov
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引用次数: 0

摘要

近年来,人们对血小板的研究产生了兴趣,血小板的功能不仅限于参与血液凝固机制。许多工作致力于研究急性和慢性酒精暴露条件下血小板的功能状态。这些研究的结果可用于开发身体酒精中毒程度的新标记物,以便随后选择一种方法对急性或慢性酒精作用引起的紊乱进行药物矫正。本文综述了近年来乙醇对血小板生物发生、丰度、形态及生化等方面的影响。对在体外和实验动物体内进行的研究以及临床观察结果进行了分析。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Effect of Ethanol on Platelet Biology

In recent years, there has been interest in the study of platelets, the functions of which, as it turned out, are not limited to their involvement in the mechanism of blood coagulation. Many works are devoted to the study of the functional state of platelets under conditions of acute and chronic alcohol exposure. The results of such studies can be useful in the development of new markers of the degree of alcohol intoxication of the body for the subsequent choice of a method for drug correction of disorders caused by acute or chronic alcohol effects. The review summarizes the results of studies on the effect of ethanol on the platelet biogenesis, abundance, morphology, and biochemistry. An analysis of studies performed both in vitro and in experimental animals in vivo, as well as the results of clinical observations, is presented.

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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
31
期刊介绍: Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry   covers all major aspects of biomedical chemistry and related areas, including proteomics and molecular biology of (patho)physiological processes, biochemistry, neurochemistry, immunochemistry and clinical chemistry, bioinformatics, gene therapy, drug design and delivery, biochemical pharmacology, introduction and advertisement of new (biochemical) methods into experimental and clinical medicine. The journal also publishes review articles. All issues of the journal usually contain solicited reviews.
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