肾移植受者感染性囊炎沙门氏菌的治疗

A. Prasetya, A. Ariane, B. Setyohadi
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引用次数: 0

摘要

沙门氏菌作为感染性滑囊炎的病原体被认为是罕见的。我们报告一例56岁男性,有肾移植史,使用霉酚酸酯、环孢菌素和甲基强的松龙作为维持药物,因左肩压痛和肿胀伴3周热入院。经调查,诊断为感染性滑囊炎。肠炎沙门氏菌是最终的病原体。他接受美罗培南1g静脉注射,每日3次,左氧氟沙星500mg静脉注射,每天1次,持续3周,然后口服环丙沙星500mg,每日2次,持续2周,口服甲硝唑500mg,每天3次,持续1周,抗生素总持续时间为5周。在随后的随访中,没有发烧复发,左肩肿胀消退,没有压痛,患者的活动范围也没有限制。由于免疫功能低下状态使治疗复杂化,治疗持续时间可能是感染性滑囊炎典型治疗的两倍。沙门氏菌作为病原体应被视为免疫功能低下的感染性滑囊炎患者的区别。关键词:免疫受损状态,感染性滑囊炎,深法氏囊,沙门氏菌,治疗持续时间。
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Management of Salmonella Septic Bursitis in Renal Transplant Recipient
Salmonella as a causative agent in septic bursitis is considered rare. We report a case of 56 years old male with history of renal transplantation and using mycophenolate mofetil, cyclosporine and methylprednisolone as maintenance, admitted due to 3-week-fever associated with tenderness and swelling on left shoulder. Upon investigation, a diagnosis of septic bursitis was established. Salmonella enteritidis as the definitive causative agent was revealed. He was treated with meropenem 1g IV three times daily and levofloxacin 500 mg IV once a day for 3 weeks, followed by oral ciprofloxacin 500 mg twice a day for 2 weeks and oral metronidazole 500 mg three times a day for 1 week with a total duration of 5 weeks of antibiotics. On the subsequent follow up there was no recurrence episode of fever and the swelling of the left shoulder subsided, no tenderness noted and the patient has no limitation of range of movement. Since immunocompromised state complicates the management, the duration of therapy may twice longer than the typical management of septic bursitis. Salmonella as etiologic agent should be considered as differential in immunocompromised patient with septic bursitis.Keywords: Immunocompromised state, septic bursitis, deep bursae, Salmonella, duration of therapy.
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