孟加拉国东南部感染严重急性呼吸综合征冠状病毒2型的单剂牛津-阿斯利康疫苗接种者的严重性评估

E. A. Rana, P. Dutta, Md. Sirazul Islam, T. Nizami, T. Das, Sharmin Chowdhury, G. B. Das
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引用次数: 1

摘要

背景和目的:包括孟加拉国在内的世界许多地区目前正在开展冠状病毒疾病(冠状病毒疾病新冠肺炎)的疫苗计划,但目前还没有接种疫苗者的健康数据。这项研究旨在调查接种了第一剂牛津-阿斯利康疫苗并感染严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)的人的健康状况。材料和方法:使用标准病毒学方法实时逆转录定量聚合酶链反应(RT-qPCR)检测严重急性呼吸系统综合征冠状病毒。在感染阶段,使用预先结构化的问卷收集了接种疫苗患者的一些健康指标。结果:共分析了6146份可疑样本,发现1752份SARS-CoV-2阳性,200人接种了第一剂新冠肺炎疫苗。在接种疫苗的人群中,一百六十五人(82.5%)没有住院,177人(88.5%)没有任何呼吸系统问题。只有8%的患者需要进一步的氧气支持,199名(99.5%)患者不需要重症监护室干预。总体而言,氧饱和度约为96.8%,在感染期间呼吸困难的持续时间不超过5天。在接种新冠肺炎疫苗的阳性人群中,113人(56.5%)和111人(55.5%)具有典型的生理味觉和嗅觉。令人惊讶的是,129人(64.5%)患有多种合并症,其中高血压(27.9%)和糖尿病(32[24.8%])最为常见。当前研究的主要结论是,199名(99.5%)接种疫苗的患者健康状况良好,RT-qPCR检测呈阴性。结论:根据本研究的结果,接种第一剂牛津-阿斯利康疫苗可显著降低新冠肺炎感染期间的健康风险。
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Severity assessment of single-dose Oxford-AstraZeneca vaccinated individuals infected with severe acute respiratory syndrome coronavirus 2 in Southeast Bangladesh
Background and Aim: A vaccine program for coronavirus illness (coronavirus disease [COVID-19]) is currently underway in numerous regions of the world, including Bangladesh, but no health data on those who have been vaccinated are available at this time. The study aimed to investigate the health condition of people who had received their first dose of the Oxford- AstraZeneca vaccine and were infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Materials and Methods: To detect SARS-CoV-2, a standard virological approach, real-time reverse transcriptase-quantitative polymerase chain reaction (RT-qPCR), was used. Several health indicators from vaccinated patients were collected using pre-structured questionnaires during the infection phase. Results: A total of 6146 suspicious samples were analyzed, and 1752 were found to be positive for SARS-CoV-2, with 200 people receiving the first dose of the COVID-19 vaccine. One hundred and sixty-five (82.5%) were not hospitalized among the vaccinated people, and 177 (88.5%) did not have any respiratory problems. Only 8% of patients required further oxygen support, and 199 (99.5%) did not require intensive care unit intervention. Overall, oxygen saturation was recorded at around 96.8% and respiratory difficulties did not extend more than 5 days during the infection period. Among the vaccinated COVID-19-positive people, 113 (56.5%) and 111 (55.5%) had typical physiological taste and smell. Surprisingly, 129 (64.5%) people had diverse comorbidities, with high blood pressure (27.9%) and diabetes (32 [24.8%]) being the most common. The major conclusion of the current study was that 199 (99.5%) of vaccinated patients survived in good health and tested negative for RT-qPCR. Conclusion: According to the findings of this study, administering the first dose of the Oxford-AstraZeneca vaccine considerably reduces health risks during the COVID-19 infection period.
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来源期刊
International Journal of One Health
International Journal of One Health Veterinary-Veterinary (all)
CiteScore
2.10
自引率
0.00%
发文量
13
审稿时长
15 weeks
期刊介绍: International Journal of One Health publishes high quality and novelty papers focusing on One Health. Review articles are highly appreciated. All articles published by International Journal of One Health are made freely and permanently accessible online. All articles to International Journal of One Health are posted online immediately as they are ready for publication.
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