麻醉辅助生殖技术(ART):叙述回顾

R. Khetarpal, V. Chatrath, Puneetpal Kaur, A. Trikha
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引用次数: 1

摘要

辅助生殖技术(ART)主要用于治疗不孕不育,包括体外受精(IVF)、细胞质内精子注射(ICSI)、配子输卵管内移植(GIFT)或受精卵输卵管内转移(ZIFT)等医疗程序。试管婴儿已经彻底改变了不孕不育的治疗方法,如今已被全世界广泛接受。试管婴儿是作为一种日托程序进行的,到目前为止,已经研究、尝试和测试了许多麻醉方案。麻醉师的作用主要是在体外受精的经阴道取卵和胚胎移植过程中发挥作用。采用各种麻醉技术,包括全身或局部麻醉、意识镇静或监控麻醉护理、患者控制镇痛、针灸和经皮神经电刺激(TENS)。麻醉管理需要仔细考虑药物对卵母细胞成熟或胚胎发育、受精和妊娠率的影响。鉴于冠状病毒病-19(新冠肺炎)大流行,ART诊所受到了影响,由于其对生殖结果的影响不明确,麻醉师需要在大流行期间对麻醉管理保持警惕和谨慎。这篇综述包括对各种麻醉选择和药物的讨论,以及它们的优点或缺点(如果有的话)。本综述的文献来源于PubMed、Medline、Cochrane Library和Google Scholar。110篇文章中有82篇讨论了25年来ART手术中不同麻醉方法的结果。
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Anaesthesia for assisted reproductive technology (ART): A narrative review
Assisted reproductive technology (ART) is used primarily to address the treatment of infertility which includes medical procedures such as in vitro fertilisation (IVF), intra-cytoplasmic sperm injection (ICSI), gamete intra-fallopian transfer (GIFT) or zygote intra-fallopian transfer (ZIFT). IVF has revolutionised infertility treatment and is nowadays widely accepted all over the world. The IVF is carried out as a daycare procedure and many anaesthetic regimens have been studied, tried and tested so far. An anaesthesiologist's role mainly comes into play during trans- vaginal oocyte retrieval and embryo transfer (ET) process of IVF. Various techniques of anaesthesia are practised which include general or regional anaesthesia, conscious sedation or monitored anaesthesia care, patient-controlled analgesia, acupuncture and transcutaneous electrical nerve stimulation (TENS). The anaesthetic management needs careful consideration of the effect of drugs on the maturation of oocytes or embryonic development, fertilisation and pregnancy rates. In view of the Coronavirus disease-19 (COVID-19) pandemic, ART clinics have been affected and due to the ambiguity of its effects on the reproductive outcome, anaesthesiologists need to be vigilant and cautious with anaesthetic management during pandemic times. This review includes a discussion of various anaesthetic options and agents along with their advantages or disadvantages if any. The literature sources for this review were obtained via PubMed, Medline, Cochrane Library and Google Scholar. The results of 82 out of 110 articles discussing different methods of anaesthesia for ART procedures over 25 years were compiled.
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