成功的管理皮肤脓肿引起的白色念珠菌在一个非常低出生体重的新生儿

IF 0.2 Q4 PEDIATRICS Journal of Clinical Neonatology Pub Date : 2022-10-01 DOI:10.4103/jcn.jcn_36_22
V. Vaddi, Medha Goyal, Dwayne Mascarenhas, A. Haribalakrishna
{"title":"成功的管理皮肤脓肿引起的白色念珠菌在一个非常低出生体重的新生儿","authors":"V. Vaddi, Medha Goyal, Dwayne Mascarenhas, A. Haribalakrishna","doi":"10.4103/jcn.jcn_36_22","DOIUrl":null,"url":null,"abstract":"Fungal sepsis is a sinister infection in the neonatal intensive care unit associated with significant mortality and neurodevelopment sequelae. Very low birth weight and very preterm neonates are often predisposed and manifestations range from mucocutaneous to invasive organ involvement. Prompt recognition and treatment with appropriate antifungal improve survival and neurodevelopmental outcomes. In this report, we describe a neonate with rare dermatological manifestation in the form of a cutaneous fungal abscess with urinary tract involvement. The diagnosis was based on budding yeast cells seen on pus smear examination and culture suggestive of Candida albicans. Risk factors included birth weight <1500 g, placement of central vascular catheter, endotracheal tube, parenteral nutrition, surgical intervention, and use of broad-spectrum antibiotics. Amphotericin B deoxycholate and incision and drainage of the abscess were done to manage the abscess successfully. This report highlights the consideration of Candida as an etiological agent for cutaneous abscesses, in case of preterms with risk factors for fungal infection. Evaluation for systemic dissemination is mandatory and management with appropriate antifungal agents is critical for survival.","PeriodicalId":45332,"journal":{"name":"Journal of Clinical Neonatology","volume":"11 1","pages":"219 - 221"},"PeriodicalIF":0.2000,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Successful management of a cutaneous abscess caused by Candida albicans in a very low birth weight neonate\",\"authors\":\"V. Vaddi, Medha Goyal, Dwayne Mascarenhas, A. Haribalakrishna\",\"doi\":\"10.4103/jcn.jcn_36_22\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Fungal sepsis is a sinister infection in the neonatal intensive care unit associated with significant mortality and neurodevelopment sequelae. Very low birth weight and very preterm neonates are often predisposed and manifestations range from mucocutaneous to invasive organ involvement. Prompt recognition and treatment with appropriate antifungal improve survival and neurodevelopmental outcomes. In this report, we describe a neonate with rare dermatological manifestation in the form of a cutaneous fungal abscess with urinary tract involvement. The diagnosis was based on budding yeast cells seen on pus smear examination and culture suggestive of Candida albicans. Risk factors included birth weight <1500 g, placement of central vascular catheter, endotracheal tube, parenteral nutrition, surgical intervention, and use of broad-spectrum antibiotics. Amphotericin B deoxycholate and incision and drainage of the abscess were done to manage the abscess successfully. This report highlights the consideration of Candida as an etiological agent for cutaneous abscesses, in case of preterms with risk factors for fungal infection. Evaluation for systemic dissemination is mandatory and management with appropriate antifungal agents is critical for survival.\",\"PeriodicalId\":45332,\"journal\":{\"name\":\"Journal of Clinical Neonatology\",\"volume\":\"11 1\",\"pages\":\"219 - 221\"},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2022-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Clinical Neonatology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/jcn.jcn_36_22\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PEDIATRICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical Neonatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/jcn.jcn_36_22","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 2

摘要

真菌性败血症是新生儿重症监护病房中一种危险的感染,与显著的死亡率和神经发育后遗症相关。非常低的出生体重和非常早产的新生儿通常易患此病,表现从皮肤粘膜到侵入性器官受累不等。及时识别和治疗适当的抗真菌药物可改善生存和神经发育结果。在这个报告中,我们描述了一个罕见的皮肤病表现形式的皮肤真菌脓肿与尿路累及新生儿。诊断是基于脓液涂片检查和培养提示白色念珠菌的芽殖酵母细胞。危险因素包括出生体重<1500 g、放置中央血管导管、气管插管、肠外营养、手术干预和使用广谱抗生素。行两性霉素B去氧胆碱及脓肿切开引流,成功控制脓肿。本报告强调考虑念珠菌作为皮肤脓肿的病原,在早产的情况下与真菌感染的危险因素。系统传播的评估是强制性的,适当的抗真菌药物管理对生存至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Successful management of a cutaneous abscess caused by Candida albicans in a very low birth weight neonate
Fungal sepsis is a sinister infection in the neonatal intensive care unit associated with significant mortality and neurodevelopment sequelae. Very low birth weight and very preterm neonates are often predisposed and manifestations range from mucocutaneous to invasive organ involvement. Prompt recognition and treatment with appropriate antifungal improve survival and neurodevelopmental outcomes. In this report, we describe a neonate with rare dermatological manifestation in the form of a cutaneous fungal abscess with urinary tract involvement. The diagnosis was based on budding yeast cells seen on pus smear examination and culture suggestive of Candida albicans. Risk factors included birth weight <1500 g, placement of central vascular catheter, endotracheal tube, parenteral nutrition, surgical intervention, and use of broad-spectrum antibiotics. Amphotericin B deoxycholate and incision and drainage of the abscess were done to manage the abscess successfully. This report highlights the consideration of Candida as an etiological agent for cutaneous abscesses, in case of preterms with risk factors for fungal infection. Evaluation for systemic dissemination is mandatory and management with appropriate antifungal agents is critical for survival.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
25
期刊介绍: The JCN publishes original articles, clinical reviews and research reports which encompass both basic science and clinical research including randomized trials, observational studies and epidemiology.
期刊最新文献
Congenital Megalourethra Presented with Renal Anomalies Glomerular Filtration Rate in Sick Neonates: A Focus on Cystatin C Neonatal Enteroviral Meningoencephalitis: Clinical and Paraclinical Characteristics of a Nosocomial Outbreak in Colombia Aphallia with Anal Stenosis and Congenital Cyanotic Heart Disease: A Rare Case Report The Effect of Plastic Wrap Use to Prevent Hypothermia on Neonatal Mortality and Morbidity in Extreme Preterm Infants
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1