延长寿命的药物去甲二氢愈创木酸抑制p300并激活自噬

IF 5.4 Q1 GERIATRICS & GERONTOLOGY NPJ Aging and Mechanisms of Disease Pub Date : 2019-07-30 DOI:10.1038/s41514-019-0037-7
T. Tezil, Manish Chamoli, Che-Ping Ng, Roman P. Simon, Victoria J. Butler, M. Jung, J. Andersen, A. Kao, E. Verdin
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Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy
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来源期刊
NPJ Aging and Mechanisms of Disease
NPJ Aging and Mechanisms of Disease Medicine-Geriatrics and Gerontology
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8 weeks
期刊介绍: npj Aging and Mechanisms of Disease is an online open access journal that provides a forum for the world’s most important research in the fields of aging and aging-related disease. The journal publishes papers from all relevant disciplines, encouraging those that shed light on the mechanisms behind aging and the associated diseases. The journal’s scope includes, but is not restricted to, the following areas (not listed in order of preference): • cellular and molecular mechanisms of aging and aging-related diseases • interventions to affect the process of aging and longevity • homeostatic regulation and aging • age-associated complications • translational research into prevention and treatment of aging-related diseases • mechanistic bases for epidemiological aspects of aging-related disease.
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