Perampanel过量用药并发呼吸衰竭1例

Journal of epilepsy research Pub Date : 2022-12-01 DOI:10.14581/jer.220012

Yangmi Park, Seondeuk Kim, D. Koo, H. Nam

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引用次数: 0

摘要

培安帕奈是一种新型的抗癫痫药物，已被用作局灶性发作癫痫的辅助治疗。到目前为止，没有任何报告记录呼吸抑制是成年人使用万帕的副作用。在此，我们报告了一名51岁的局灶性癫痫患者，在意外服用66mg的帕痛后出现2型呼吸衰竭。每当需要给患者服用高剂量的帕痛时，临床医生应考虑呼吸系统损害的可能性。

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A Case of Perampanel Overdose Presenting with Respiratory Failure

Perampanel is a novel antiepileptic drug that has been used as an adjunctive treatment for focal-onset seizures. No reports to date have documented respiratory suppression as a side effect of perampanel in adults. Herein, we report a 51-year-old man with focal epilepsy presented with type 2 respiratory failure after accidently consuming of 66 mg of perampanel. Clinicians should consider the possibility of respiratory compromise whenever a high dose of perampanel needs to be administered to patients.

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Journal of epilepsy research

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