Basic and clinical research progress of psychological pharmacology： a brand-new discipline

Psychological pharmacology is a brand-new discipline that studies the interaction between psychological state and drugs，explores general rules of the effects of mental state on drug activity，and promotes rational use of drugs in clinical practice.Evidence showed that depression could affect the levels of endogenous substances，drug metabolizing enzymes and drug transport protein，thus influencing drug metabolism and efficacy.In clinical practice，medication recognition might affect drug choice and medication compliance of patients.The application of placebo might achieve positive treatment outcomes in certain patients.These research results indicate that attention should be paid to the psychological state of patients in drug treatment.In accordance with changes of physiological and psychological changes of patients，therapeutic regimens should be duly adjusted.Rational drug use education and psychological support should be provided to patients，so that patients’ psychological burden could be relieved and therapeutic efficacy improved.