Natural Existence and Bioactivity of Flavonoids: Synthetic Strategies and Mechanistic Pathways

A class of chemicals known as flavonoids is widely distributed in various portions of plants, cereals, and vegetables. They have varied phenolic structures and these flavonoid molecules are known for the well-being improvement in living things. Today, a wide range of pharmaceutical, medicinal, & cosmetic materials possessed these key ingredients, known as flavonoids. Flavonoids can modulate the bioactivity of essential enzymes & their properties such as anti-mutagenic, anti-inflammatory, anti-oxidative, & anti-carcinogenic. The current patterns of flavonoid in research & development helps in the identification, isolation, characterization, & functions of flavonoids as well as their applications for better biological activities. In this article, we have discussed the natural existence and structural frameworks of the different classes of potential bioactive flavonoids. In addition to this, different synthetic strategies, and their mechanistic pathways for the preparation of different classes of flavonoids are also discussed thoroughly here. Owing to its tremendous natural existence and bioactivity, more research is still needed to further explore the usefulness of flavonoids for human wellness. The major challenge with the study of such flavonoids is the diversity of molecular structures & scarcity of data on their bioavailability. However, this article will be helpful for understanding the chemical aspect and several potential bioactivities of flavonoids