印度中部一家三级护理教学医院类风湿性关节炎患者的药物处方模式和生活质量:一项横断面研究

A. Siddiqui, Shadma H. Quazi, Sharjeel H. Khan, Tanaji R. Shende
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摘要

目的:药物使用研究的主要目标是帮助患者负责任地使用药物。慢性炎症性疾病类风湿性关节炎(RA)是一种包括长期残疾的疾病。抗病性抗风湿药物(DMARD)是预防关节损伤的主要治疗方法。这项研究的目的是检查用于治疗RA的药物的处方趋势。方法:与骨科联合,在一家三级护理医院进行了一项为期6个月的横断面观察性研究。目前的研究共包括90名符合纳入和排除要求的患者。以病例报告的形式收集患者的数据,并对其进行检查,以确定参与研究的所有90名患者的处方模式。在这项研究中,68.8%的女性患者以女性为主,而受该疾病影响的男性患者为31.1%。40-60岁年龄组的患者(63.3%)最常见,其次是61-70岁(26.6%)。两种DMARD(甲氨蝶呤和羟氯喹)的组合在90%的患者中最常见。仅4.4%的患者需要三联DMARD。在28.8%的患者中,依托西是最常用的止痛药,其次是依托多拉克,占16.6%。结论:RA对女性的影响比男性更大。与单药治疗和三药治疗相比,甲氨蝶呤和HCQ的DMARD组合是最常用的。药物使用研究向处方医生提供反馈,并提高他们对正确使用药物的认识。
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Drug prescription patterns and quality of life in rheumatoid arthritis patients at a tertiary care teaching hospital in Central India: A cross-sectional study
Objective: Drug use research's main goal is to assist patients in using medications responsibly. The chronic inflammatory disease rheumatoid arthritis (RA) is a condition comprising long-term disability. Disease-modifying antirheumatic drugs (DMARDs) are the mainstay of therapy preventing joint damage. The study's aim was to examine the prescription trends for medications used to treat RA. Methodology: In conjunction with the orthopedic department, a cross-sectional observational study was carried out in a tertiary care hospital for 6 months. The current study included 90 patients in total who met the inclusion and exclusion requirements. Data from patients were collected in a case report format and examined to determine the prescription pattern in all 90 patients participated in the study. Female preponderance was seen in the study with 68.8% of female patients compared to 31.1% of male patients affected by the disease. Patients of the age group of 40–60 years (63.3%) were most commonly affected, followed by 61–70 years (26.6%). A combination of two DMARDs, methotrexate and hydroxychloroquine (HCQ), was the most common in 90% of patients. Triple-DMARD combination was required only in 4.4% of patients. Etoricoxib was most the commonly prescribed analgesic in 28.8% of patients, followed by etodolac in 16.6%. Conclusions: RA affects females more often than males. DMARD combination of methotrexate and HCQ was the most commonly used compared to monotherapy and triple-drug therapy. Drug utilization studies give the prescriber feedback and raise their awareness of the proper usage of medications.
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