皮肤病学中的真菌基因组学

Y. Lee, S. Lee, Ji-Min Seo, Min Ji Kang, D. Yu
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引用次数: 0

摘要

到目前为止,已经对数百个真菌基因组进行了测序,还有更多的基因组正在进行中。最近开发的尖端技术产生了大量的数据,皮肤病学中的真菌基因组学领域也因此得到了长足的发展。方法的改进扩大了皮肤病学大规模生态学研究的范围,包括生物多样性评估和真菌的基因组鉴定。在此,我们旨在简要介绍皮肤病学领域真菌基因组学的生物信息学方法。我们描述了真菌基因组学的历史和基本概念,并提出了基于测序的真菌鉴定技术,包括通过当前的系统发育分析确定的皮肤癣菌的修订分类群列表。最后,我们讨论了皮肤科真菌基因组学的新趋势,如下一代测序。
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Fungal Genomics in Dermatology
To date, hundreds of fungal genomes have been sequenced, and many more are underway. Recently developed cutting-edge techniques generate very large amounts of data, and the field of fungal genomics in dermatology has consequently evolved substantially. Methodological improvements have broadened the scope of large-scale ecological studies in dermatology, including biodiversity assessments and genomic identification of fungi. Here, we aimed to provide a brief introduction to bioinformatic approaches to fungal genomics in the field of dermatology. We described the history and basic concepts of fungal genomics and presented sequencing-based techniques for fungal identification, including a list of the revised taxa of dermatophytes, as determined by current phylogenetic analysis. Finally, we discussed the emerging trends in fungal genomics in dermatology, such as next-generation sequencing.
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来源期刊
Journal of Mycology and Infection
Journal of Mycology and Infection Medicine-Infectious Diseases
CiteScore
0.20
自引率
0.00%
发文量
13
期刊介绍: The Journal of mycology and infection (Acronym: JMI, Abbreviation: J Mycol Infect) aims to publish articles of exceptional interests in the field of medical mycology. The journal originally was launched in 1996 as the Korean Journal of Medical Mycology and has reformed into the current state beginning on March of 2018. The contents of the journal should elucidate important microbiological fundamentals and provide qualitative insights to respective clinical aspects. JMI underlines the submission of novel findings and studies in clinical mycology that are enriched by analyses achieved through investigative methods. The journal should be of general interests to the scientific communities at large and should provide medical societies with advanced breadth and depth of mycological expertise. In addition, the journal supplements infectious diseases in adjunct to the field of mycology to address a well-rounded understanding of infectious disorders. The Journal of mycology and infection, which is issued quarterly, in March, June, September and December each year, published in English. The scope of the Journal of mycology and infection includes invited reviews, original articles, case reports, letter to the editor, and images in mycology. The journal is compliant to peer-review/open access and all articles undergo rigorous reviewing processes by our internationally acknowledged team of editorial boards. The articles directed to publication should encompass in-depth materials that employ scholastic values of mycology and various infectious diseases. Articles responding to critical methodology and outcomes which have potential to enhance better understanding of mycology and infectious diseases are also suitable for publication.
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