糖尿病与非糖尿病眼超声乳化术后角膜变化的比较

Asmaa Elminshawy, H. Hegazy, M. Aly
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Ophthalmological examinations, including uncorrected and best-corrected visual acuity (BCVA), slit lamp to examine anterior and posterior corneal surfaces, tear film breakup time test (TBUT), anterior chamber depth by IOL Master (Topcon ALADDIN HW2.0), and specular microscopy (Topcon SP-1P, made In Japan), were done preoperatively and at 1 week, 1 month, and 3 months postoperatively. Results Significant differences were found between preoperative and postoperative periods in both groups regarding BCVA, TBUT, CCT, endothelial cell density (ECD), coefficient of variation, and hexagonal cells, except that changes became insignificant with respect to CCT at 3 months in nondiabetic and at 1 week and 3 months in diabetic and in CD at 1 month in healthy patients. Conclusion There were significant changes in BCVA, TBUT, CCT, and ECD after phacoemulsification in the diabetic and healthy groups. 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引用次数: 0

摘要

背景与目的超声乳化术中角膜内皮易受手术损伤。一些研究报道了糖尿病和健康患者超声乳化术后角膜变化的不同结果。目的是评估和比较糖尿病患者和健康患者在正常超声乳化术前后角膜前泪膜、角膜前后表面、内皮细胞变化和角膜中央厚度(CCT)的变化。选取40例拟行白内障手术的患者40只眼,分为1组(非糖尿病患者20只眼)和2组(糖尿病患者20只眼)。术前、术后1周、1个月、3个月进行眼科检查,包括未矫正和最佳矫正视力(BCVA)、裂隙灯检查角膜前后表面、泪膜破裂时间测试(TBUT)、IOL Master (Topcon ALADDIN HW2.0)前房深度、镜面显微镜(Topcon SP-1P,日本制造)。结果两组患者术前和术后BCVA、TBUT、CCT、内皮细胞密度(ECD)、变异系数、六角形细胞差异均有统计学意义,但非糖尿病患者3个月、糖尿病患者1周和3个月、健康患者1个月的CCT变化不显著。结论糖尿病组与健康组超声乳化术后BCVA、TBUT、CCT、ECD均有显著变化。超声乳化术后1个月,糖尿病患者的CCT恢复明显延迟。
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Comparison of corneal changes after phacoemulsification in diabetic and nondiabetic eyes
Background and aim Endothelium of the cornea is susceptible to surgical trauma during phacoemulsification from ultrasound energy. Several studies have reported various results of corneal changes after phacoemulsification in diabetic and healthy patients. The aim was to evaluate and compare changes in precorneal tear film, anterior and posterior corneal surfaces, endothelial cell changes, and central corneal thickness (CCT) between diabetic and healthy patients before and after uneventful phacoemulsification. Patients and methods A total of 40 eyes of 40 patients who were scheduled for cataract surgery were divided into group 1 (20 eyes in nondiabetic patients) and group 2 (20 eyes in diabetic patients). Ophthalmological examinations, including uncorrected and best-corrected visual acuity (BCVA), slit lamp to examine anterior and posterior corneal surfaces, tear film breakup time test (TBUT), anterior chamber depth by IOL Master (Topcon ALADDIN HW2.0), and specular microscopy (Topcon SP-1P, made In Japan), were done preoperatively and at 1 week, 1 month, and 3 months postoperatively. Results Significant differences were found between preoperative and postoperative periods in both groups regarding BCVA, TBUT, CCT, endothelial cell density (ECD), coefficient of variation, and hexagonal cells, except that changes became insignificant with respect to CCT at 3 months in nondiabetic and at 1 week and 3 months in diabetic and in CD at 1 month in healthy patients. Conclusion There were significant changes in BCVA, TBUT, CCT, and ECD after phacoemulsification in the diabetic and healthy groups. There was a significant delay in the recovery of CCT 1 month after phacoemulsification in the diabetic compared with healthy individuals.
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