Mitochondrial DNA Mutations and its Role in the Genesis of Renal Diseases an Update

The errors in the Mitochondrial DNA affects tissues that require highly dependent of energy to work properly like the Brain, the Heart, the Muscle and the Kidneys, the defects in the genesis of ATP affects this tissues sometimes involving more than one organ, therefore myophaties, encephalophaties, can be associated with renal diseaseswich rare in adults and more frequently in children in whom arefrequently unsuspected and underestimated. Their prevavalence in the general population is also underestimated and may be as high as 1-2:10,000 live births.